Skip to main content

Table 2 OCT characteristics of coronary plaques in the culprit vessel according to the presence or absence of DMC

From: Microvascular complications identify a specific coronary atherosclerotic phenotype in patients with type 2 diabetes mellitus

Characteristics

Plaques of patients with DMC (n = 82)

Plaques of patients without DMC (n = 87)

p value

Clinical characteristics

 Plaque vessel

0.108

  LAD [n, (%)]

55 (67.0)

73 (84.0)

 

  LCx [n, (%)]

18 (22.0)

7 (8.0)

 

  RCA [n, (%)]

9 (11.0)

7 (8.0)

 

 Plaque type

< 0.001

  Fibrous plaque [n, (%)]

53 (64.6)

27 (31.0)

 

  Lipid plaque [n, (%)]

29 (35.4)

60 (69.0)

 

 FCT (µm) [median (IQR)]

100.0 (72.5 – 110.0)

100.0 [86.3; 110.0]

0.389

 Lipid arc mean (°) [median (IQR)]

168.2 [123.0; 213.5]

185.5 [143.9; 228.3]

0.439

 Lipid length (mm) (mean ± standard deviation)

8.7 ± 2.9

9.4 ± 3.7

0.345

 Lipid index (mm) (mean ± standard deviation)

1531.2 ± 692.7

1653.1 ± 861.3

0.441

 TCFA [n, (%)]

7 (8.5)

13 (14.9)

0.199

 Calcifications [n, (%)]

65 (79.3)

35 (40.2)

< 0.001

  Calcific arc mean (°) (mean ± standard deviation)

165.1 ± 76.6

109.1 ± 107.5

< 0.001

  Calcific length (mm) (mean ± standard deviation)

10.1 ± 5.0

8.0 ± 4.1

0.003

  Calcific depth (mm) (mean ± standard deviation)

0.79 ± 0.26

0.52 ± 0.24

< 0.001

 Spotty calcifications [n, (%)]

15 (18.3)

39 (44.8)

0.003

 Plaque length (mm) (mean ± standard deviation)

15.8 ± 7.2

13.5 ± 5.9

0.014

 Healed plaque phenotype [n, (%)]

18 (22.0)

8 (9.2)

0.018

 Macrophages [n, (%)]

32 (39.0)

36 (41.4)

0.776

 Microvessels [n, (%)]

30 (36.6)

29 (33.3)

0.686

 Cholesterol crystals [n, (%)]

24 (29.3)

22 (25.3)

0.599

 MLA (mm2) (mean ± standard deviation)

3.5 ± 2,1

4.0 ± 2.2

0.127

 AS (mm2) (mean ± standard deviation)

60.9 ± 11.0

58.3 ± 12.4

0.137

  1. Bold values are reported for variables that are statistically significant (p < 0.05)
  2. DMC diabetic microvascular complications, OCT optical coherence tomography, LAD left anterior descending artery, LCx left circumflex, RCA right coronary artery, FCT fibrous cap thickness, IQR interquartile range, TCFA thin cap fibroatheroma, MLA minimal lumen area, AS area stenosis