Table 6 Multivariable analysis of factors associated with in-hospital mortality with infective endocarditis, among all patients according to sex

40–66 years old

1

1

1

67–75 years old

1.34 (1.02–1.76)

1.14 (0.73–1.78)

1.35 (1.07–1.69)

 ≥ 76 years old

2.22 (1.71–2.89)

1.87 (1.24–2.84)

2.12 (1.7–2.64)

Acute renal disease

2.12 (1.73–2.6)

2.19 (1.65–2.9)

1.98 (1.68–2.33)

Chronic renal disease

1.22 (1.01–1.51)

1.18 (1–1.39)

Congestive heart failure

1.96 (1.72–2.42)

2.11 (1.79–3.20)

2.01 (1.68–2.87

Ischemic heart disease

1.27 (1.04–1.55)

1.41 (1.14–1.72)

1.34 (1.11–1.57)

Septic arterial embolism

3.73 (2.07–6.73)

1.78 (1.24–2.56)

Cardiogenic shock

4.35 (2.59–7.28)

5.5 (2.24–13.5)

4.02 (2.58–6.25)

Dialysis

1.8 (1.27–2.56)

3.4 (2.07–5.58)

1.91 (1.44–2.53)

Heart valve surgery (aortic, mitral, tricuspid, pulmonary)

0.74 (0.56–0.97)

Mechanical ventilation

3.49 (2.65–4.6)

2.63 (1.73–4)

3.06 (2.44–3.84)

Pacemaker implantation

0.34 (0.2–0.57)

0.34 (0.22–0.53)

Staphylococcus bacteremia

1.29 (1.05–1.58)

1.49 (1.26–1.74)

Streptococcus bacteremia

0.44 (0.32–0.59)

0.39 (0.26–0.58)

0.43 (0.34–0.55)

Female sex

NA

NA

1.31 (1.11–1.54)

T2DM

0.87 (0.72–1.05)

0.93 (0.72–1.2)

0.92 (0.8–1.07)