Table 4 Distribution of study covariates and hospital outcomes of MEN AND WOMEN with T2DM with infective endocarditis in Spain (2016–2020), before and after propensity score matching (PSM)
BEFORE PSM | AFTER PSM | |||||
|---|---|---|---|---|---|---|
T2DM Men | T2DM Women | p-value | T2DM Men | T2DM Women | p-value | |
N, (incidence per 100,000 subjects per year) | 1829 (23.29) | 839 (11.91) | < 0.001 | 839 | 839 | NA |
Age, mean (SD) | 71.61 (9.88) | 75.58 (9) | < 0.001 | 76.29 (7.65) | 75.58 (9) | 0.081 |
40–66 years old, n (%) | 543 (29.69) | 122 (14.54) | < 0.001 | 81 (9.65) | 122 (14.54) | 0.004 |
67–75 years old, n (%) | 590 (32.26) | 264 (31.47) | 302 (36) | 264 (31.47) | ||
≥ 76 years old, n (%) | 696 (38.05) | 453 (53.99) | 456 (54.35) | 453 (53.99) | ||
Acute renal disease, n (%) | 463 (25.31) | 205 (24.43) | 0.626 | 200 (23.84) | 205 (24.43) | 0.775 |
Chronic renal disease, n (%) | 514 (28.1) | 257 (30.63) | 0.181 | 247 (29.44) | 257 (30.63) | 0.594 |
Congestive heart failure, n (%) | 294 (16.07) | 146 (17.4) | 0.391 | 133 (15.85) | 146 (17.4) | 0.394 |
COPD, n (%) | 253 (13.83) | 35 (4.17) | < 0.001 | 40 (4.78) | 35 (4.17) | 0.554 |
Dementia, n (%) | 31 (1.69) | 34 (4.05) | < 0.001 | 25 (2.98) | 34 (4.05) | 0.233 |
Atrial fibrillation, n (%) | 545 (29.8) | 319 (38.02) | < 0.001 | 309 (36.83) | 319 (38.02) | 0.614 |
COVID-19, n (%) | 6 (0.33) | 6 (0.72) | 0.165 | 6 (0.72) | 6 (0.72) | 0.999 |
Ischemic heart disease, n (%) | 506 (27.67) | 114 (13.59) | < 0.001 | 132 (15.73) | 114 (13.59) | 0.214 |
Previous aortic valve disease, n (%) | 483 (26.41) | 206 (24.55) | 0.309 | 192 (22.88) | 206 (24.55) | 0.422 |
Previous mitral valve disease, n (%) | 402 (21.98) | 268 (31.94) | < 0.001 | 260 (30.99) | 268 (31.94) | 0.674 |
Previous pulmonic valve disease, n (%) | 2 (0.11) | 2 (0.24) | 0.424 | 1 (0.12) | 2 (0.24) | 0.563 |
Previous tricuspid valve disease, n (%) | 104 (5.69) | 94 (11.2) | < 0.001 | 73 (8.7) | 94 (11.2) | 0.087 |
Prosthetic valve carriers, n (%) | 173 (9.46) | 83 (9.89) | 0.724 | 84 (10.01) | 83 (9.89) | 0.935 |
CCI index, mean (SD) | 1.47 (1.13) | 1.41 (0.99) | 0.170 | 1.26 (1.05) | 1.41 (0.99) | 0.004 |
Periannular complications / atrioventricular block, n (%) | 122 (6.67) | 45 (5.36) | 0.196 | 53 (6.32) | 45 (5.36) | 0.405 |
Septic arterial embolism, n (%) | 67 (3.66) | 35 (4.17) | 0.525 | 34 (4.05) | 35 (4.17) | 0.902 |
Cardiogenic shock, n (%) | 35 (1.91) | 14 (1.67) | 0.662 | 9 (1.07) | 14 (1.67) | 0.294 |
Dialysis, n (%) | 118 (6.45) | 64 (7.63) | 0.263 | 41 (4.89) | 64 (7.63) | 0.020 |
Heart valve surgery (aortic, mitral, tricuspid, pulmonary), n (%) | 336 (18.37) | 121 (14.42) | 0.012 | 123 (14.66) | 121 (14.42) | 0.890 |
Mechanical ventilation, n (%) | 207 (11.32) | 87 (10.37) | 0.468 | 65 (7.75) | 87 (10.37) | 0.061 |
Pacemaker implantation, n (%) | 121 (6.62) | 41 (4.89) | 0.083 | 50 (5.96) | 41 (4.89) | 0.332 |
LOHS, Median (IQR) | 19 (25) | 18 (25) | 0.257 | 19 (26) | 18 (25) | 0.329 |
IHM, n (%) | 302 (16.51) | 190 (22.65) | < 0.001 | 151 (18.00) | 190 (22.65) | 0.018 |