Table 1 Incidence, clinical characteristics and in-hospital outcomes of patients hospitalized with infective endocarditis in Spain from 2016 to 2020 according to T2DM status
2016 | 2017 | 2018 | 2019 | 2020 | p-value | ||
|---|---|---|---|---|---|---|---|
N, (incidence per 100,000 subjects per year) | T2DM | 468 (15.29) | 534 (17.45) | 538 (18.06) | 615 (21.21) | 513 (17.69) | < 0.001 |
No T2DM | 1385 (6.12) | 1411 (6.23) | 1615 (6.93) | 1518 (6.33) | 1361 (5.68) | 0.111 | |
N, (incidence per 100,000 women per year) | T2DM | 154 (10.64) | 165 (11.4) | 160 (11.36) | 196 (14.3) | 164 (11.96) | 0.056 |
No T2DM | 458 (3.82) | 481 (4.01) | 577 (4.69) | 490 (3.87) | 463 (3.66) | 0.385 | |
N, (incidence per 100,000 men per year) | T2DM | 314 (19.47) | 369 (22.88) | 378 (24.07) | 419 (27.42) | 349 (22.84) | 0.003 |
No T2DM | 927 (8.7) | 930 (8.72) | 1038 (9.44) | 1028 (9.07) | 898 (7.92) | 0.161 | |
Age, mean (SD) | T2DM | 72.94 (10.09) | 72.5 (9.62) | 72.78 (9.62) | 72.53 (9.99) | 73.66 (9.58) | 0.298 |
No T2DM | 69.76 (13.23) | 69.26 (13.19) | 70.16 (13.54) | 69.47 (13.23) | 69.99 (12.7) | 0.330 | |
CCI index, mean (SD) | T2DM | 1.26 (1.07) | 1.4 (1) | 1.5 (1.13) | 1.5 (1.1) | 1.56 (1.11) | < 0.001 |
No T2DM | 1.06 (1.04) | 1.16 (1.05) | 1.15 (1.04) | 1.1 (1.03) | 1.2 (1.08) | 0.006 | |
Previous aortic valve disease, n (%) | T2DM | 115 (24.57) | 146 (27.34) | 118 (21.93) | 175 (28.46) | 135 (26.32) | 0.109 |
No T2DM | 356 (25.7) | 412 (29.2) | 469 (29.04) | 446 (29.38) | 455 (33.43) | 0.001 | |
Previous mitral valve disease, n (%) | T2DM | 110 (23.5) | 121 (22.66) | 145 (26.95) | 156 (25.37) | 138 (26.9) | 0.378 |
No T2DM | 381 (27.51) | 396 (28.07) | 457 (28.3) | 432 (28.46) | 430 (31.59) | 0.138 | |
Previous pulmonic valve disease, n (%) | T2DM | 0 (0) | 3 (0.56) | 0 (0) | 1 (0.16) | 0 (0) | 0.080 |
No T2DM | 4 (0.29) | 5 (0.35) | 3 (0.19) | 1 (0.07) | 5 (0.37) | 0.430 | |
Previous tricuspid valve disease, n (%) | T2DM | 24 (5.13) | 28 (5.24) | 44 (8.18) | 60 (9.76) | 42 (8.19) | 0.011 |
No T2DM | 74 (5.34) | 97 (6.87) | 138 (8.54) | 126 (8.3) | 140 (10.29) | < 0.001 | |
Prosthetic valve carriers, n (%) | T2DM | 59 (12.61) | 44 (8.24) | 57 (10.59) | 53 (8.62) | 43 (8.38) | 0.085 |
No T2DM | 132 (9.53) | 140 (9.92) | 144 (8.92) | 123 (8.1) | 128 (9.4) | 0.483 | |
LOHS, Median (IQR) | T2DM | 19 (27) | 17 (27) | 18.5 (24) | 19 (25) | 18 (23) | 0.633 |
No T2DM | 19 (24) | 19 (27) | 19 (27) | 19 (24) | 19 (23) | 0.994 | |
IHM, n (%) | T2DM | 89 (19.02) | 104 (19.48) | 93 (17.29) | 104 (16.91) | 102 (19.88) | 0.622 |
No T2DM | 226 (16.32) | 207 (14.67) | 280 (17.34) | 276 (18.18) | 249 (18.3) | 0.058 |