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Table 2 Clinical outcomes occurred during follow-up

From: Results of a prospective observational study of autologous peripheral blood mononuclear cell therapy for no-option critical limb-threatening ischemia and severe diabetic foot ulcers

 

Study population (n = 50)

At 1 year

 Dead, n (%)

16 (32.0)

Major amputation, n (%)

 All patients (n = 50)

8 (16.0)

 Alive at 1 year (n = 34)

7 (20.6)

Ulcer healing, n (%)

  All patients (n = 50)

22 (44.0)

  Alive at 1 year (n = 34)

21 (61.8)

Ulcer healing without a major amputation, n (%)

  All patients (n = 50)

17 (34.0)

  Alive at 1 year (n = 34)

16 (47.1)

Estimated* time to healing without a major amputation (days), mean ± SE

257 ± 17

At the end of follow-up

 Follow-up time (years), median [IQR]

1.46 [0.55–2.01]

 Dead, n (%)

24 (48.0)

 Major amputation, n (%)

  All patients (n = 50)

9 (18.0)

  Alive at the end of follow-up (n = 26)

5 (19.3)

 Walking capability, n (%)

  All patients (n = 50)

30 (60.0)

  Alive at the end of follow-up (n = 26)

23 (88.5)

 Ulcer healing, n (%)

  All patients (n = 50)

30 (60.0)

  Alive at the end of follow-up (n = 26)

23 (88.5)

 Ulcer healing without a major amputation, n (%)

  All patients (n = 50)

25 (50.0)

  Alive at the end of follow-up (n = 26)

19 (73.1)

 Estimated* time to healing without a major amputation (days), mean ± SE

345 ± 39

  1. IQR interquartile range [1st quartile-3rd quartile], SE standard error
  2. *Time was estimated with Kaplan–Meier approach, considering deaths and drop-out as censored