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Table 2 Summary of the CCL7 in diabetes mellitus in this review article

From: CCL7 as a novel inflammatory mediator in cardiovascular disease, diabetes mellitus, and kidney disease

Diabetes mellitus

References

Type 1 diabetes

CCL7 (T lymphocyte exosomes) ↑

Recruitment of immune cells↑/β-cell apoptosis ↑/Diastolic abnormality

[51,52,53,54]

CCL7 (Islets cells) ↑

CXCL1, CXCL5, and CCL7 ↑

[55]

Type 2 diabetes

CCL7 (Adipose tissue) ↑

Interferon regulatory factor 5 transcripts were positively associated with CCL7

[56, 57]

Neutrophil infiltration↑/Insulin resistance↑

[59,60,61]

Diabetes and ischemic stroke

Serum CCL7 ↑

[58]