Characteristics | Without DM | With DM | p value | ||||||
---|---|---|---|---|---|---|---|---|---|
All (A) | non-cardiac injury | cardiac injury | p value | All (B) | non-cardiac injury | cardiac injury | p value | A vs. B | |
C3 (g/l) | 1.0 (0.9–1.2) | 1.0 (0.9–1.2) | 1.0 (0.9–1.1) | 0.287 | 1.0 (0.9–1.1) | 1.0 (0.9–1.2) | 0.9 (0.8–1.1) | 0.001 | 0.208 |
C4 (g/l) | 0.3 (0.2–0.3) | 0.3 (0.2–0.3) | 0.3 (0.2–0.3) | 0.015 | 0.3 (0.2–0.3) | 0.3 (0.2–0.3) | 0.3 (0.2–0.3) | 0.209 | 0.23 |
IgA (g/l) | 2.3 (1.7–2.9) | 2.3 (1.7–2.9) | 2.4 (2.0–3.0) | 0.082 | 2.7 (2.0–3.6) | 2.6 (1.9–3.4) | 3.1 (2.1–3.8) | 0.065 |  < 0.001 |
IgE (IU/ml) | 42.0 (9.2–106.3) | 42.0 (9.2–107.8) | 40.5 (9.2–90.5) | 0.928 | 54.0 (9.2–13.0) | 54.0 (9.2–143.0) | 50.5 (9.2–95.8) | 0.289 | 0.157 |
IgG (g/l) | 11.7 (10.0–13.9) | 11.7 (10.0–13.9) | 11.8 (9.6–13.9) | 0.835 | 12.3 (10.4–14.9) | 12.1 (10.1–14.7) | 12.8 (11.4–15.1) | 0.205 | 0.009 |
IgM (g/l) | 0.9 (0.7–1.2) | 0.9 (0.7–1.2) | 0.9 (0.6–1.2) | 0.249 | 0.9 (0.7–1.3) | 0.9 (0.7–1.2) | 1.0 (0.8–1.4) | 0.069 | 0.695 |
WBC (× 109/l) | 5.2 (3.9–7.0) | 5.1 (3.9–6.8) | 6.2 (4.4–10.0) | 0.001 | 6.2 (4.7–8.3) | 5.8 (4.5–7.6) | 7.0 (5.2–11.4) | 0.008 |  < 0.001 |
LYM (× 109/l) | 1.1 (0.8–1.5) | 1.1 (0.8–1.5) | 0.8 (0.6–1.3) |  < 0.001 | 0.9 (0.6–1.2) | 1.0 (0.6–1.3) | 0.7 (0.5–1.0) |  < 0.001 |  < 0.001 |
NEU (× 109/l) | 3.3 (2.4–5.1) | 3.3 (2.3–4.8) | 4.7 (3.0–7.8) |  < 0.001 | 4.7 (3.3–6.9) | 4.2 (2.8–6.1) | 5.7 (4.2–9.5) |  < 0.001 |  < 0.001 |
Baso (× 109/l) | 0.01 (0.01–0.02) | 0.01 (0.01–0.02) | 0.01 (0.01–0.02) | 0.332 | 0.01 (0.01–0.03) | 0.01 (0.01–0.03) | 0.01 (0.01–0.02) | 0.137 | 0.196 |
EOS (× 109/l) | 0.02 (0.00–0.06) | 0.02 (0.00–0.06) | 0.01 (0.00–0.04) | 0.226 | 0.01 (0.00–0.06) | 0.01 (0.00–0.08) | 0.00 (0.00–0.01) |  < 0.001 | 0.032 |
CD3 + T cells (cells/ul) | 657.5 (442.5–940.5) | 677.0 (457.5–962.5) | 452.0 (249.0–619.0) |  < 0.001 | 480.0 (283.5–79.0) | 558.0 (322.0–844.0) | 338.0 (237.8–41.4) |  < 0.001 |  < 0.001 |
CD3 + CD4 + T cells (cells/ul) | 392.5 (246.5–576.0) | 407.0 (260.5–596.5) | 265.0 (158.0–414.0) |  < 0.001 | 292.0 (182.5–84.0) | 365.0 (193.5–35.0) | 203.0 (125.3–16.0) |  < 0.001 | 0.033 |
CD3 + CD8 + T cells (cells/ul) | 223.0 (138.0–334.8) | 228.0 (147.0–338.0) | 165.0 (74.0–232.0) |  < 0.001 | 149.0 (80.0–260.5) | 176.0 (100.5–263.5) | 110.0 (59.0–204.3) |  < 0.001 |  < 0.001 |
CD4/CD8 ratio | 1.8 (1.2–2.6) | 1.8 (1.3–2.5) | 1.8 (1.1–2.7) | 0.942 | 1.9 (1.3–2.9) | 1.9 (1.3–2.8) | 2.0 (1.2–3.5) | 0.693 | 0.033 |
CD19 + B cells (cells/ul) | 135.0 (90.0–205.0) | 138.0 (92.0–206.0) | 112.0 (66.0–158.0) | 0.004 | 119.0 (77.5–189.5) | 131.0 (83.5–225.0) | 102.5 (60.0–169.8) | 0.007 | 0.044 |
CD16 + CD56 + NK cells (cells/ul) | 118.0 (77.0–185.0) | 117.0 (77.0–183.0) | 145.0 (59.0–252.0) | 0.438 | 109.0 (63.0–171.0) | 115.0 (68.0–176.5) | 79.0 (45.5–170.8) | 0.057 | 0.018 |
IL2 (pg/ml) | 3.8 (3.4–4.1) | 4.0 (3.0–4.0) | 4.0 (3.0–4.0) | 0.542 | 3.7 (3.3–4.1) | 4.0 (3.0–4.0) | 4.0 (3.0–4.0) | 0.659 | 0.516 |
IL4 (pg/ml) | 3.4 (3.0–3.9) | 4.0 (3.0–4.0) | 4.0 (3.0–4.0) | 0.663 | 3.4 (3.0–3.8) | 4.0 (3.0–4.0) | 4.0 (3.0–4.0) | 0.337 | 0.604 |
IL5 (pg/ml) | 2.2 (2.1–2.3) | 2.2 (2.1–2.3) | 2.3 (2.1–2.3) | 0.992 | 2.2 (2.1–2.4) | 2.3 (2.2–2.4) | 2.0 (2.0–2.3) | 0.19 | 0.804 |
IL6 (pg/ml) | 6.0 (3.1–11.7) | 6.0 (3.0–11.0) | 9.5 (5.0–22.3) | 0.007 | 10.7 (5.5–25.1) | 8.0 (5.0–19.0) | 25.0 (13.8–90.0) |  < 0.001 |  < 0.001 |
IL10 (pg/ml) | 5.5 (4.7–6.7) | 6.0 (5.0–7.0) | 6.0 (5.0–8.5) | 0.022 | 6.3 (5.1–8.0) | 6.0 (5.0–8.0) | 8.0 (6.0–9.0) |  < 0.001 |  < 0.001 |
TNF-α (pg/ml) | 3.4 (2.9–4.7) | 3.0 (3.0–5.0) | 3.0 (3.0–4.0) | 0.35 | 3.3 (2.9–5.7) | 3.0 (3.0–6.0) | 3.0 (3.0–5.3) | 0.611 | 0.447 |
γ-interferon (pg/ml) | 3.5 (3.0–4.3) | 3.0 (3.0–4.0) | 3.0 (3.0–4.0) | 0.001 | 3.4 (3.0–4.3) | 3.0 (3.0–4.0) | 3.5 (3.0–4.3) | 0.008 |  < 0.001 |
CRP (mg/l) | 4.8 (2.2–28.4) | 4.0 (2.0–21.0) | 36.0 (7.0–65.0) | 0.009 | 4.4 (2.3–51.9) | 4.0 (2.0–32.4) | 39.0 (4.0–196.0) | 0.032 | 0.567 |
PCT (ng/ml) | 0.1 (0.0–0.10) | 0.0 (0.0–0.0) | 0.0 (0.0–0.0) |  < 0.001 | 0.1 (0.1–0.3) | 0.0 (0.0–0.0) | 0.0 (0.0–1.0) |  < 0.001 |  < 0.001 |
NLR | 3.0 (1.9–5.4) | 2.8 (1.8–5.1) | 5.1 (3.5–12.5) |  < 0.001 | 5.9 (3.0–10.5) | 4.3 (2.6–9.3) | 8.8 (6.3–14.7) |  < 0.001 |  < 0.001 |