Fig. 4

Incidence rate and hazard ratio of cardiovascular disease and all-cause mortality incidence rate by the combination of cumTyG and time course of TyG index accumulation. cumTyG cumulative triglyceride glucose index, TyG index triglyceride glucose index. The four categories of combination of cumTyG and TyG slope were as follows: <M, ≥ 0: cumTyG < Median (34.44 × years), and TyG slope ≥ 0; <M, < 0: cumTyG < Median, and TyG slope < 0; ≥M, ≥ 0: cumTyG ≥ Median, and TyG slope ≥ 0; ≥M, < 0: cumTyG ≥ Median, and TyG slope  < 0. Adjusted for age, sex, education, income, drinking status, smoking status, physical activity, history of hypertension, diabetes, dyslipidemia, antihypertensive agents, antidiabetic agents, lipid-lowering agents, body mass index, systolic blood pressure, diastolic blood pressure, fasting blood glucose, total cholesterol, estimated glomerular filtration rate, and high sensitivity C-reactive protein