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Fig. 9 | Cardiovascular Diabetology

Fig. 9

From: Dapagliflozin reduces the vulnerability of rats with pulmonary arterial hypertension-induced right heart failure to ventricular arrhythmia by restoring calcium handling

Fig. 9

Assessment of APD alternans. a Representative recording of SCA-APD from a CTL heart. ΔAPD map and an AP recording from a single pixel at 80 ms BCL (position shown with a triangle on the map). b Example of the SDA-APD from an MCT heart. ΔAPD map and AP recordings from two pixels at 100 ms BCL. c The BCL threshold for SCA-APD alternans in each group. Each point represents the result from one heart. The horizontal lines show the median values for BCL that induce the SCA-APD alternans. d Inducibility of SDA-APD in each group. SCA-APD spatially concordant alternans action potential duration, SDA-APD spatially discordant alternans action potential duration, AP action potential, BCL basic cycle length. n = 10 per group. One-way ANOVA or χ2 tests. *p < 0.05, **p < 0.01, ***p < 0.001

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