Association between the triglyceride–glucose index and severity of coronary artery disease

Table 4 Associations between the TyG index and severity of CAD according to different diabetes statuses

Glucose metabolism state	Model 1			Model 2			Model 3
Glucose metabolism state	OR	95% CI	P-value	OR	95% CI	P-value	OR	95% CI	P-value
NGR
TyG index	0.825	0.559–1.216	0.331	0.929	0.617–1.398	0.723	0.846	0.551–1.299	0.444
T1	Reference			Reference			Reference
T2	1.206	0.787–1.848	0.389	1.246	0.759–2.045	0.385	1.167	0.710–1.916	0.543
T3	0.660	0.393–1.109	0.117	0.739	0.400–1.366	0.335	0.684	0.371–1.262	0.225
Pre-DM
TyG index	1.210	0.910–1.607	0.189	1.412	1.043–1.903	0.023	1.367	1.000–1.867	0.049
T1	Reference			Reference			Reference
T2	1.161	0.844–1.597	0.359	1.230	0.859–1.761	0.258	1.217	0.860–1.724	0.268
T3	1.351	0.927–1.968	0.118	1.613	1.050–2.477	0.029	1.541	1.013–2.344	0.043
DM
TyG index	1.162	0.931–1.449	0.185	1.230	0.982–1.542	0.072	1.214	0.963–1.530	0.100
T1	Reference			Reference			Reference
T2	1.282	0.857–1.918	0.226	1.341	0.871–2.064	0.182	1.265	0.849–1.884	0.249
T3	1.300	0.901–1.875	0.161	1.390	0.934–2.069	0.104	1.321	0.921–1.914	0.141

Model 1: unadjusted
Model 2: adjusted for age and sex
Model 3: adjusted for sex, age, BMI, smoking, drinking, hypertension, eGFR, antiplatelet drug use, antilipidemic drug use, and antihypertensive drug use
TyG triglyceride–glucose, CAD coronary artery disease, OR odds ratio, CI confidence interval, BMI body mass index, eGFR estimated glomerular filtration rate, NGR normoglycemia, Pre-DM pre-diabetes mellitus, DM diabetes mellitus

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