| Groups | P value | |||
---|---|---|---|---|---|
MACE (N = 75) | Non-MACE (N = 124) | ||||
Baseline | 12Â months | Baseline | 12Â months | ||
Age (y) | 81 ± 15 | – | 76 ± 12 | – | 0.432 |
Males, n (%) | 60 (80) | Â | 101 (81.4) | Â | 0.951 |
Smoking, n (%) | 32 (42.7) | 18 (24) | 18 (14.5)# | 9 (7.5) |  < 0.001 |
Hypertension, n (%) | 58 (77.3) | – | 90 (72.6) | – | 0.383 |
Dyslipidemia, n (%) | 73 (97.3) | – | 119 (96) | – | 0.909 |
Statins, n (%) | 73 (97.3) | 74 (98.7) | 118 (95.2) | 121 (97.6) | 0.943 |
ABI | 0.49 (0.09) | – | 0.54 (0.09) | – | 0.799 |
Diabetes, n (%) | 34 (45.3) | – | 45 (36.3) | – | 0.206 |
BMI (kg/m2) | 27.98 ± 3.72 | 27.56 ± 3.55 | 28.21 ± 3.9 | 28 ± 3.7 | 0.922 |
SBP (mmHg) | 144 ± 24 | 140 ± 25 | 135 ± 24# | 134 ± 28 | 0.108 |
DBP (mmHg) | 85 ± 8 | 84 ± 7 | 85 ± 9 | 85 ± 10 | 0.998 |
TChol (mg/dl) | 176 ± 49 | 167 ± 46 | 165 ± 41 | 159 ± 46 | 0.967 |
HDL-C (mg/dl) | 38 ± 8 | 39 ± 7 | 41 ± 11 | 42 ± 9 | 0.781 |
LDL-C (mg/dl) | 130 ± 43 | 104 ± 37* | 102 ± 35# | 92 ± 22* | 0.043 |
TG (mg/dl) | 132 ± 61 | 120 ± 61 | 109 ± 42 | 101 ± 42 | 0.070 |
Creatinine (mg/dl) | 1.42 ± 0.55 | 1.35 ± 0.52 | 1.27 ± 0.47 | 1.20 ± 0.37 | 0.980 |
GFR (mL/min/1.73 m2) | 47 ± 12 | 50 ± 12 | 55 ± 19 | 58 ± 19 | 0.926 |
FPG (mg/dl) | 155 ± 45 | 135 ± 45* | 146 ± 41 | 128 ± 28 | 0.900 |
HbA1c (%)a | 7.9 ± 1.4 | 7.3 ± 1.1 | 7.3 ± 1.3 | 6.9 ± 0.9 | 0.131 |
hsCRP (mg/L) | 8.05 ± 2.67 | 4.79 ± 1.27 | 5.55 ± 2.12# | 2.98 ± 1.05 |  < 0.001 |
OPN (ng/ml) | 96.45 ± 40.12 | 78.1 ± 38.29 | 73.05 ± 29.88# | 51.66 ± 18.77* |  < 0.001 |
OPG (pmol/L) | 13.29 ± 3.23 | 10.86 ± 3* | 9.04 ± 3.56# | 6.12 ± 2.34* |  < 0.001 |