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Table 1 Clinical and laboratory characteristics of both, peripheral artery disease group (PADG) and control group (COG) at baseline

From: Association of serum levels of osteopontin and osteoprotegerin with adverse outcomes after endovascular revascularisation in peripheral artery disease

 

PADG

(n = 203)

COG

(n = 78)

P value

Age (y)

77 ± 15

71 ± 13

0.0256

Males, n (%)

174 (85.7)

65 (83.3)

0.949

Smoking, n (%)

50 (24.6)

14 (18.2)

0.002

Hypertension, n (%)

151 (74.4)

13 (16.7)

 < 0.001

Dyslipidemia, n (%)

197 (97)

36 (46.2)

 < 0.001

Statins, n (%)

193 (95.1)

20 (25.6)

 < 0.001

ABI

0.51 (0.11)

1.1 (0.1)

 < 0.001

Diabetes, n (%)

81 (39.9)

7 (9)

 < 0.001

BMI (kg/m2)

28.12 ± 3.67

26.5 ± 3.98

0.101

SBP (mmHg)

138 ± 22

121 ± 13

 < 0.001

DBP (mmHg)

85 ± 10

77 ± 8

0.387

TChol (mg/dl)

175 ± 53

158 ± 49

0.076

HDL-C (mg/dl)

40 ± 9

49 ± 12

 < 0.001

LDL-C (mg/dl)

112 ± 43

89 ± 22

0.065

TG (mg/dl)

114 ± 58

101 ± 33

0.405

Creatinine (mg/dl)

1.31 ± 0.41

0.98 ± 0.22

0.021

GFR (mL/min/1.73 m2)

51 ± 15

98 ± 9

0.002

FPG (mg/dl)

139 ± 41

100 ± 15

 < 0.001

HbA1c (%)a

7.5 ± 1.3

6.5 ± 0.8

-

hsCRP (mg/L)

7.88 ± 2.11

1.06 ± 0.39

 < 0.001

OPN (ng/ml)

79.99 ± 38.29

35.21 ± 14.84

 < 0.001

OPG (pmol/L)

9.89 ± 2.85

3.47 ± 1.95

 < 0.001

  1. Data are expressed as means ± SD
  2. n number of patients; BMI body-mass index; SBP systolic blood pressure, DBP diastolic blood pressure; TChol total cholesterol; TG triglycerides; FPG fasting plasma glucose; hsCRP high-sensitivity C-Reactive Protein; OPN osteopontin; OPG osteoprotegerin
  3. aHbA1c was measured only in diabetic patients. due to the very small subgroup of diabetic controls we did not statistical difference for HbA1c
  4. P value of differences between groups