Fig. 3

Subgroup analyses of the relationship between cumulative triglyceride-glucose (TyG) index and MACEs. The study population was stratified by age (< 65 years vs. ≥ 65 years), sex (male vs. female), and body mass index (BMI; < 30 kg/m² vs. ≥ 30 kg/m²). Adjustments were made for age, sex, education level, race, smoking status, drinking status, years of hypertension diagnosis, years of diabetes diagnosis, depression, body mass index, systolic blood pressure, diastolic blood pressure, heart rate, history of CVD, plasma total cholesterol, HbA1c, LDL-C, eGFR, statin, insulin, non-dihydropyridine calcium channel blockers, dihydropyridine calcium channel blockers, thiazolidinediones, and thiazide diuretics treatment at the baseline level. BMI body mass index, CI confidence interval, CVD cardiovascular disease, eGFR estimated glomerular filtration rate, HbA1c glycated hemoglobin, HR hazards ratio, LDL-C low-density lipoprotein cholesterol, MACEs major adverse cardiovascular events, SD standard deviation, TyG triglyceride-glucose