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Fig. 2 | Cardiovascular Diabetology

Fig. 2

From: The link between gestational diabetes and cardiovascular diseases: potential role of extracellular vesicles

Fig. 2

Schematic illustration of the potential role of EVs in mediating epigenetic signals in fetal metabolic reprogramming in GDM. In GDM, excess nutrients are supplied to the fetus via placental transfer which leads to exposure of fetal cells to the altered metabolic milieu. The fetal cells respond to the altered uterine microenvironment by epigenetic alterations in metabolic genes. EVs can potentially mediate the transfer of epigenetic signals between fetal cells thus mediating the change in the epigenetic landscape, and susceptibility to future diseases

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Cardiovascular Diabetology

ISSN: 1475-2840