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Table 1 Proportion of events and their incidence by fifths of the geometric mean of each person’s kidney disease index

From: A novel kidney disease index reflecting both the albumin-to-creatinine ratio and estimated glomerular filtration rate, predicted cardiovascular and kidney outcomes in type 2 diabetes

 

Overall

N = 9115

Quintile 1

N = 1823

Quintile 2

N = 1823

Quintile 3

N = 1823

Quintile 4

N = 1823

Quintile 5

N = 1823

P

Median KDI (10—90)

0.26 (0.20–0.37)

0.20 (0.16–0.21)

0.23 (0.22–0.24)

0.26 (0.25–0.27)

0.30 (0.28–0.32)

0.37 (0.33–0.47)

 

Median eGFR (10—90)

74.9 (48.8–106.8)

97.3 (73.0–126.2)

85.2 (67.2–109.9)

76.2 (59.6–98.2)

67.6 (51.7–86.9)

51.8 (33.5–69.9)

 

Median ACR (10—90)

1.8 (0.3–29.8)

0.4 (0.1–1.3)

1.1 (0.4–3.7)

1.8 (0.6–9.0)

4.0 (1.0–27.0)

18.1 (2.2–109.4)

 

MACE

 N (%)

1161 (12.7)

149 (8.2)

175 (9.6)

194 (10.6)

264 (14.5)

379 (20.8)

< 0.001

 N/100py

2.51

1.54

1.84

2.08

2.90

4.43

 

Death

 N (%)

1045 (11.5)

108 (5.9)

140 (7.7)

167 (9.2)

223 (12.2)

407 (22.3)

< 0.001

 N/100py

2.19

1.09

1.43

1.74

2.36

4.56

 

Kidney composite

 N (%)

1226 (13.5)

161 (8.8)

136 (7.5)

213 (11.7)

274 (15.0)

442 (24.2)

< 0.001

 N/100py

2.71

1.68

1.43

2.31

3.08

5.55

 
  1. The kidney composite includes new macroalbuminuria, a sustained decline in eGFR ≥ 40%, or chronic kidney replacement therapy; the P value is from the chi-square test for trend
  2. GM geometric mean; 10–90 the tenth and 90th percentile boundaries; ACR albumin-to-creatinine ratio; eGFR estimated glomerular filtration rate