Table 2 Risk of incident cardiovascular disease and mortality by baseline TyG index

Cardiovascular disease

 Continuous (per unit)

158/4,574

3.20 (2.51, 4.09)

 < 0.001

2.21 (1.63, 2.98)

 < 0.001

1.96 (1.44, 2.66)

 < 0.001

Quartiles

 Quartile 1 (≤ 7.5)

12/1,144

Reference

-

Reference

–

Reference

–

 Quartile 2 (> 7.5, ≤ 7.8)

33/1,143

2.75 (1.42, 5.33)

0.002

2.33 (1.20, 4.54)

0.012

2.41 (1.23, 4.69)

0.009

 Quartile 3 (> 7.8, ≤ 8.1)

35/1,143

3.06 (1.58, 5.91)

0.001

2.19 (1.12, 4.28)

0.021

2.19 (1.12, 4.29)

0.021

 Quartile 4 (> 8.1)

78/1,144

6.73 (3.63, 12.47)

 < 0.001

3.70 (1.92, 7.12)

 < 0.001

3.67 (1.90, 7.06)

0.001

 p for trend

 < 0.001

 < 0.001

 < 0.001

All-cause mortality

 Continuous (per unit)

246/4,574

2.12 (1.71, 2.61)

 < 0.001

1.98 (1.56, 2.52)

 < 0.001

1.85 (1.45, 2.36)

 < 0.001

Quartiles

 Quartile 1 (≤ 7.5)

36/1,144

Reference

–

Reference

–

Reference

–

 Quartile 2 (> 7.5, ≤ 7.8)

52/1,143

1.42 (0.93, 2.18)

0.103

1.34 (0.87, 2.05)

0.180

1.32 (0.86, 2.03)

0.193

 Quartile 3 (> 7.8, ≤ 8.1)

61/1,143

1.68 (1.11, 2.55)

0.013

1.58 (1.03, 2.41)

0.032

1.54 (1.00, 2.35)

0.045

 Quartile 4 (> 8.1)

97/1,144

2.56 (1.73, 3.79)

 < 0.001

2.27 (1.48, 3.46)

 < 0.001

2.18 (1.43, 3.34)

 < 0.001

 p for trend

 < 0.001

 < 0.001

 < 0.001