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Table 2 The association between overall prediabetes, IFG, IGT and elevated HbA1c and increased baPWV in middle-aged and old adults

From: Age-specific difference in the association between prediabetes and subclinical atherosclerosis: an analysis of a chinese prospective cohort study

 

Age < 60 years

Age ≥ 60 years

P for interaction

Young:Old ROR

OR (95% CI) in Model 1

OR (95% CI) in Model 2

OR (95% CI) in Model 1

OR (95% CI) in Model 2

NGR

1.00

1.00

1.00

1.00

Prediabetes

1.44 (1.07–1.94)

1.36 (1.00-1.86)

0.82 (0.63–1.08)

0.89 (0.67–1.18)

0.003

1.87 (1.25–2.81)

IFG

1.64 (1.16–2.31)

1.71 (1.20–2.44)

0.95 (0.68–1.33)

0.98 (0.70–1.39)

0.006

1.99 (1.22–3.23)

IGT

1.30 (0.94–1.81)

1.31 (0.92–1.86)

0.59 (0.44–0.80)

0.61 (0.44–0.83)

< 0.001

2.67 (1.70–4.20)

Elevated HbA1c

1.46 (1.09–1.95)

1.38 (1.02–1.87)

1.04 (0.80–1.36)

1.13 (0.86–1.48)

0.067

1.45 (0.98–2.16)

  1. The ORs of prediabetes were calculated compared to normal glucose regulation. The ORs of IFG were calculated compared to normal FPG, and those of IGT were estimated compared to normal 2 h-PPG, and those of elevated HbA1c were calculated compared to normal HbA1c. Model 1: adjust for age and sex; Model 2: adjust for age, sex, SBP, DBP, BMI, TG, LDL-C, HDL-C, uric acid, eGFR, smoking, drinking and anti-hypertensive drug
  2. OR, odds ratio; CI, confidence interval; ROR, ratio of odds ratio; baPWV, branchial-ankle pulse wave velocity; NGR, normal glucose regulation; IFG, impaired fasting glucose; IGT, impaired glucose tolerance; HbA1c, glycated hemoglobin; SBP, systolic blood pressure; DBP, diastolic blood pressure; BMI, body mass index; TG, triglyceride; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; eGFR, estimated glomerular filtration rate