HDL functionality in type 1 diabetes: enhancement of cholesterol efflux capacity in relationship with decreased HDL carbamylation after improvement of glycemic control

Table 2 Univariate correlation study

Changes after intervention in:	CEC		Carbamylated HDLs
	r	P-value	r	P-value
CEC	1	N.A	−0.411	0.034
Carbamylated HDLs	−0.411	0.034	1	N.A
BMI	0.105	0.60	−0.087	0.67
HbA_1c	−0.403	0.038	0.141	0.48
Serum triglycerides	−0.068	0.73	0.109	0.59
Serum HDL-cholesterol	0.193	0.33	−0.494	0.010
MPO	−0.005	0.98	0.153	0.44
eGFR	−0.080	0.69	−0.094	0.23
Urea	0.109	0.59	0.158	0.32
HDL-phospholipids	0.189	0.34	0.173	0.39
HDL-proteins	0.059	0.77	−0.446	0.021
HDL-triglycerides	0.123	0.54	−0.516	0.006
HDL-esterified cholesterol	−0.169	0.40	0.032	0.87
HDL-free cholesterol	0.147	0.46	−0.492	0.010
HDL-apoAI	−0.140	0.48	−0.080	0.69

r corresponds to the Spearman correlation coefficient. BMI body mass index, CEC cholesterol efflux capacity, eGFR estimated glomerular filtration rate, MPO myeloperoxidase, N.A. not applicable.

ISSN: 1475-2840