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Table 3 Univariate and multivariate Cox regression analysis for predicting the primary endpoint

From: Adjustment of the GRACE score by the triglyceride glucose index improves the prediction of clinical outcomes in patients with acute coronary syndrome undergoing percutaneous coronary intervention

Variables

Univariate analysis

Multivariate analysis

HR

95% CI

P value

HR

95% CI

P value

GRACE score

1.0253

1.0182 to 1.0325

< 0.0001

1.0202

1.0117 to 1.0288

< 0.0001

Female

1.5832

1.0334 to 2.4255

0.0348

1.3103

0.8403 to 2.0431

0.2332

BMI

0.9528

0.8841 to 1.0268

0.2050

   

Smoking

0.7895

0.5222 to 1.1936

0.2623

   

Previous PCI

1.3968

0.7428 to 2.6268

0.2997

   

Hypertension

1.3202

0.8409 to 2.0728

0.2274

   

Diabetes mellitus

1.2838

0.8433 to 1.9544

0.2440

   

TyG index

1.4961

1.1437 to 1.9571

0.0033

1.6028

1.1900 to 2.1588

0.0019

HDL-C

0.9716

0.4767 to 1.9805

0.9368

   

LDL-C

0.9249

0.7572 to 1.1297

0.4441

   

bSS

1.0537

1.0324 to 1.0755

< 0.0001

1.0244

0.9992 to 1.0502

0.0574

ICR

1.9863

1.2077 to 3.2669

0.0069

1.2399

0.7231 to 2.1259

0.4345

LVEF

0.9448

0.9269 to 0.9629

< 0.0001

0.9773

0.9548 to 1.0003

0.0530

AMI

1.9438

1.2533 to 3.0148

0.0030

0.8695

0.5326 to 1.4196

0.5761

β-blockers

0.9299

0.5975 to 1.4473

0.7475

   

Diuretics

3.2982

2.1419 to 5.0787

< 0.0001

1.5413

0.9234 to 2.5727

0.0979

ACEI/ARB

1.2600

0.8330 to 1.9057

0.2737

   

Insulin

1.4863

0.7696 to 2.8704

0.2380

   
  1. The primary endpoint was defined as a composite of all-cause death and nonfatal myocardial infarction. HR, hazard ratio; CI, confidence interval; GRACE score, Global Registry of Acute Coronary Events score; the TyG index, the triglyceride-glucose index; BMI, body mass index; FBG, fasting blood glucose; HDL-C, high density lipoprotein; LDL-C, low density lipoprotein; CTO, chronic total occlusion; ICR, incomplete revascularization; LVEF, left ventricular ejection fraction; AMI, acute myocardial infarction; bSS, baseline SYNTAX score; rSS, residual SYNTAX score; ACEI/ARB, angiotensin converting enzyme inhibitor/angiotensin receptor blocker