Fig. 11

Microclots and platelets in two individuals with Long COVID/PASC. A Representative micrographs of microclots in an untreated patient diagnosed with Long COVID/PASC, suffering from the condition for 11 months. The plasma was stained with thioflavin T (ThT); B Platelet hyperactivation of the same patient, where PAC-1 and CD62PE were used to mark platelets. C In this patient, cellular debris in the haematocrit was noted—here such cellular debris is shown in a tile scan. D, E Microclot presence and platelets from a patient who was on self-administrated aspirin (anti-platelet) treatment before blood collection, where major microclots were noted, but the platelets were minimal hyperactivated, possibly due to the use of anti-platelet therapy