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Table 1 Baseline characteristics of 19924 hypertensive patients according to the trajectories of TyG index from 2006 to 2010

From: Triglyceride-glucose index trajectory and stroke incidence in patients with hypertension: a prospective cohort study

Variables

Low-Stable

Moderate low-stable

Moderate high-stable

Elevated-stable

Elevated-increasing

P

N

2483

9666

5759

1741

275

–

Age, years

59.38 ± 11.35

57.29 ± 11.35

55.76 ± 10.71

54.49 ± 10.13

51.88 ± 9.29

 < 0.01

Male n (%)

2029 (81.72)

7886 (81.58)

4708 (81.75)

1478 (84.89)

241 (87.64)

 < 0.01

Heart rate, beats/min

72.72 ± 10.62

73.97 ± 10.91

75.51 ± 11.29

77.89 ± 11.77

78.69 ± 10.54

 < 0.01

BMI, kg/m2

24.31 ± 3.27

25.61 ± 3.33

26.68 ± 3.31

26.99 ± 3.29

27.01 ± 3.30

 < 0.01

SBP, mmHg

140.83 ± 19.51

140.69 ± 19.11

142.21 ± 18.73

143.69 ± 19.16

142.43 ± 17.13

 < 0.01

DBP, mmHg

87.89 ± 10.71

88.89 ± 10.71

90.09 ± 10.68

90.93 ± 11.11

91.65 ± 10.38

 < 0.01

Total cholesterol, mmol/L

4.67 ± 0.87

4.95 ± 0.92

5.23 ± 1.03

5.43 ± 1.17

6.44 ± 1.79

 < 0.01

hs-CRP, mmol/L

1.26 (0.62, 3.01)

1.04 (0.40, 2.60)

1.30 (0.50, 3.10)

1.60 (0.70, 3.70)

1.61 (0.90, 3.72)

 < 0.01

TyG in 2006

7.94 ± 0.34

8.55 ± 0.37

9.22 ± 0.44

9.84 ± 0.52

10.45 ± 0.60

 < 0.01

TyG in 2008

7.91 ± 0.32

8.56 ± 0.36

9.15 ± 0.42

9.87 ± 0.53

10.67 ± 0.63

 < 0.01

TyG in 2010

7.97 ± 0.32

8.53 ± 0.38

9.13 ± 0.44

9.81 ± 0.49

10.86 ± 0.61

 < 0.01

Current smoker, n (%)

800 (32.22)

3416 (35.34)

2251 (39.09)

794 (45.61)

136 (49.45)

 < 0.01

Current drinker, n (%)

698 (28.11)

2983 (30.86)

2126 (36.92)

761 (43.71)

134 (48.73)

 < 0.01

Active physical activity, n (%)

415 (16.71)

1573 (16.27)

865 (15.02)

230 (13.21)

42 (15.27)

 < 0.01

Senior high school or above, n (%)

351 (14.14)

1865 (19.29)

1240 (21.53)

376 (21.60)

64 (23.27)

 < 0.01

Atrial fibrillation, n (%)

33 (1.33)

90 (0.93)

43 (0.75)

10 (0.57)

0 (0.00)

0.02

Diabetes mellitus, n (%)

47 (1.89)

648 (6.70)

1296 (22.50)

793 (45.55)

176 (64.01)

 < 0.01

Hypoglycemic drugs, n (%)

19 (0.77)

231 (2.39)

482 (8.37)

284 (16.31)

65 (23.64)

 < 0.01

Anti-hypertensive drugs, n (%)

449 (18.08)

1969 (20.37)

1487 (25.82)

504 (28.95)

103 (37.45)

 < 0.01

Lipid-lowering drugs, n (%)

9 (0.36)

82 (0.85)

114 (1.98)

53 (3.04)

13 (4.73)

 < 0.01

  1. TyG triglyceride-glucose index, BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, hs-CRP high-sensitivity C-reactive protein