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Fig. 6 | Cardiovascular Diabetology

Fig. 6

From: Glycated ACE2 reduces anti-remodeling effects of renin-angiotensin system inhibition in human diabetic hearts

Fig. 6

A Evaluation of Angiotensin-1–9 (Ang-1–9), Ang 1–7, MAS1, and NFAT activation molecule 1 (NFAM1) content in explanted hearts (HTX) at week 1 (Basal) and week 48 (follow-up) from HTX, in nondiabetic and diabetic patients. *P < 0.05 vs nondiabetics, §P < 0.05 vs basal values. B Levels of Ang-1–9, Ang 1–7, MAS1, and NFAM1 assessed in explanted hearts (HTX) at week 1 (Basal) and week 48 (Follow-up) from HTX, in the diabetic patients with good glycemic control (HbA1c < 7%) and diabetic patients with poor glycemic control (HbA1c ≥ 7%) *P < 0.05 vs diabetic patients in good glycemic control (< 7%), §P < 0.05 vs basal values

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Cardiovascular Diabetology

ISSN: 1475-2840