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Fig. 5 | Cardiovascular Diabetology

Fig. 5

From: Glycated ACE2 reduces anti-remodeling effects of renin-angiotensin system inhibition in human diabetic hearts

Fig. 5

ACE2 and GlycACE2 expression in human cardiomyocytes. A Representative images of Western blotting analysis of ACE2 and GlycACE2 in explanted heart tissue, basal and follow-up biopsies from nondiabetic and diabetic patients with poor (HbA1c > 7%) or good (HbA1c < 7%) glycemic control. ACE2 and Glyc ACE2 levels were normalized using α-Tubulin. Glyc ACE2 levels in B nondiabetic and diabetic patients and C diabetic patients with HbA1c < 7% and diabetic patients with HbA1c > 7%. Analysis was performed by ImageJ 1.52n software; values were expressed as percentage and data were shown as box and whisker plots using GraphPad Prism 9.1.2. software. *P < 0.05 vs nondiabetic patients; †P < 0.05 vs diabetic patients in good glycemic control (< 7%), §P < 0.05 vs basal values

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Cardiovascular Diabetology

ISSN: 1475-2840