Triglyceride-glucose index linked to all-cause mortality in critically ill patients: a cohort of 3026 patients

Table 2 Cox proportional hazard ratios (HR) for all-cause mortality

Categories	Events (%)	Model 1			Model 2			Model 3
Categories	Events (%)	HR (95% CI)	P-value	P for trend	HR (95% CI)	P-value	P for trend	HR (95% CI)	P-value	P for trend
Hospital death
Continuous variable per 1 unit		1.29 (1.12–1.48)	< 0.001		1.26 (1.09–1.46)	0.002		2.19 (1.59–3.03)	< 0.001
Quartile^a	350 (11.57)			< 0.001			0.004			< 0.001
Q1 (N = 756)	57 (7.54)	Ref.			Ref.			Ref.
Q2 (N = 755)	85 (11.26)	1.57 (1.12–2.20)	0.008		1.57 (1.12–2.21)	0.009		1.70 (1.06–2.70)	0.027
Q3 (N = 758)	102 (13.46)	1.73 (1.25–2.39)	< 0.001		1.69 (1.22–2.35)	0.002		2.08 (1.29–3.33)	0.002
Q4 (N = 757)	106 (14.00)	1.75 (1.27–2.42)	< 0.001		1.69 (1.20–2.37)	0.003		2.80 (1.53–5.13)	< 0.001
ICU death
Continuous variable per 1 unit		1.31 (1.12–1.53)	< 0.001		1.21 (1.02–1.43)	0.029		1.72 (1.18–2.52)	0.005
Quartile	258 (8.53)			0.002			0.030			0.036
Q1 (N = 756)	42 (5.56)	Ref.			Ref.			Ref.
Q2 (N = 755)	59 (7.81)	1.46 (0.98–2.17)	0.060		1.44 (0.96–2.15)	0.074		1.52 (0.88–2.64)	0.136
Q3 (N = 758)	77 (10.16)	1.75 (1.20–2.54)	0.004		1.65 (1.13–2.42)	0.010		1.88 (1.09–3.24)	0.023
Q4 (N = 757)	80 (10.57)	1.78 (1.22–2.58)	0.003		1.55 (1.04–2.29)	0.030		1.95 (0.96–3.99)	0.066

Model 1: unadjusted
Model 2: adjusted for age, sex, ethnicity, first care unit
Model 3: adjusted for age, sex, ethnicity, first care unit, SOFA score, LODS score, white blood cell, red blood cell, hemoglobin, serum sodium, serum potassium, total cholesterol, low-density lipoprotein, high-density lipoprotein, albumin, serum creatinine, coronary heart disease, heart failure, hypertension, dyslipidemia, diabetes, chronic obstructive pulmonary disease, respiratory failure, liver disease, chronic kidney disease, acute kidney injury, sepsis, cancer
^aTyG index: Q1 (6.23–8.65), Q2 (8.65–9.08), Q3 (9.08–9.59), Q4 (9.59–12.43)

ISSN: 1475-2840