Table 3 Placebo-adjusted mean (95% confidence interval) changes in cardiometabolic variables from baseline to 6 months by racial group (adjusted models)
Cardiometabolic variable | Racial group | Mean change (95% CI) | Racial difference P–value vs. Asians | Overall race × treatment interaction P–value |
|---|---|---|---|---|
HbA1c (%) | Black | − 0.63 (− 0.77, − 0.46) | 0.82 | 0.10 |
|  | Other Race | − 0.66 (− 0.79, − 0.54) | 0.80 |  |
|  | White | − 0.54 (− 0.58, − 0.49) | 0.10 |  |
|  | Asian | − 0.63 (− 0.75, − 0.53) |  |  |
HbA1c (mmol/mol) | Black | − 6.8 (− 8.5, − 5.1) | 0.82 | 0.10 |
|  | Other Race | − 7.3 (− 8.7, − 5.9) | 0.80 |  |
|  | White | − 5.9 (− 6.4, − 5.4) | 0.10 |  |
|  | Asian | − 7.0 (− 8.3, − 5.8) |  |  |
Systolic blood pressure (mmHg) | Black | 0.0 (− 2.0, 2.0) | 0.19 | 0.47 |
|  | Other Race | − 1.8 (− 3.5, − 0.2) | 0.87 |  |
|  | White | − 1.6 (− 2.1, − 1.0) | 0.96 |  |
|  | Asian | − 1.6 (− 3.2, − 0.1) |  |  |
Diastolic blood pressure (mmHg) | Black | 1.2 (− 0.1, 2.4) | 0.19 | 0.52 |
|  | Other Race | 0.7 (− 0.3, 1.7) | 0.50 |  |
| Â | White | 0.4 (0.1, 0.7) | 0.73 | Â |
|  | Asian | 0.2 (− 0.7, 1.2) |  |  |
Pulse rate (beats/min) | Black | 2.1 (0.9, 3.3) | 0.006 | 0.016 |
| Â | Other Race | 2.8 (1.8, 3.8) | 0.048 | Â |
| Â | White | 2.7 (2.4, 3.1) | 0.003 | Â |
| Â | Asian | 4.2 (3.3, 5.1) | Â | Â |
Serum LDL cholesterol (mmol/L) | Black | 0.02 (− 0.08, 0.13) | 0.27 | 0.58 |
|  | Other Race | − 0.05 (− 0.13, 0.04) | 0.89 |  |
|  | White | − 0.06 (− 0.09, − 0.03) | 0.94 |  |
|  | Asian | − 0.05 (− 0.13, 0.03) |  |  |
Serum HDL cholesterol (mmol/L) | Black | 0.00 (− 0.03, 0.04) | 0.65 | 0.83 |
|  | Other Race | 0.01 (− 0.02, 0.03) | 0.66 |  |
|  | White | 0.00 (− 0.01, 0.01) | 0.36 |  |
|  | Asian | 0.01 (− 0.01, 0.04) |  |  |
Serum triglycerides (mmol/L) | Black | 0.0 (− 0.2, 0.2) | 0.92 | 0.19 |
|  | Other Race | 0.0 (− 0.1, 0.2) | 0.99 |  |
|  | White | − 0.1 (− 0.2, –0.1) | 0.13 |  |
|  | Asian | 0.0 (− 0.1, 0.2) |  |  |