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Table 1 Baseline characteristics

From: Short and long-term prognosis of admission hyperglycemia in patients with and without diabetes after acute myocardial infarction: a retrospective cohort study

 

Patients without diabetes

Patients with T2DM

Hyperglycemia diabetes vs non-diabetes

Non-hyperglycemia (n = 1091)

Hyperglycemia (n = 1179)

p-value

Non-hyperglycemia (n = 635)

Hyperglycemia (n = 425)

p-value

p-value

Patient characteristics

 Age, years

  

0.736

  

0.485

0.000

  ≤ 55

590 (54)

629 (53)

 

258 (41)

182 (43)

  

  > 55

501 (46)

550 (47)

 

377 (59)

243 (57)

  

 Male sex

903 (83)

965 (82)

0.582

456 (72)

279 (66)

0.035

< 0.0001

 BMI, Kg/m2

25.95 [23.53, 28.23]

26.06 [23.73, 27.98]

0.713

26.16 [24.22, 28.52]

26.06 [23.57, 28.65]

0.264

0.547

 Ethnic

  

0.424

  

0.611

0.167

  Uyghur

946 (87)

1015 (86)

 

555 (87)

373 (88)

  

  Han

120 (11)

144 (12)

 

73 (11)

50 (12)

  

  Others

25 (2)

20 (2)

 

7 (1)

2 (0)

  

 Smoking status

  

0.498

  

0.091

< 0.0001

  Never smoker

545 (50)

607 (51)

 

380 (60)

282 (66)

  

  Former smoker

470 (43)

481 (41)

 

203 (32)

111 (26)

  

  Current smoker

76 (7)

91 (8)

 

52 (8)

32 (8)

  

 Drinking

144 (13)

156 (13)

1.000

61 (10)

41 (10)

1.000

0.058

 Killip class

  

< 0.0001

  

0.002

< 0.0001

  < II

543 (50)

448 (38)

 

223 (35)

110 (26)

  

  ≥ II

548 (50)

731 (62)

 

412 (65)

315 (74)

  

 LVEF, %

  

0.193

  

0.537

0.003

  < 40

92 (8)

119 (10)

 

90 (14)

66 (16)

  

  ≥ 40

999 (92)

1060 (90)

 

545 (86)

359 (84)

  

 STEMI

730 (67)

885 (75)

< 0.0001

399 (63)

277 (65)

0.473

0.000

Medical history

 Hypertension

393 (36)

439 (37)

0.571

328 (52)

220 (52)

1.000

< 0.0001

 Stroke

149 (14)

143 (12)

0.287

91 (14)

61 (14)

1.000

0.236

 Prior CAD

20 (2)

32 (3)

0.206

22 (3)

12 (3)

0.599

0.864

 COPD

50 (5)

42 (4)

0.242

34 (5)

19 (4)

0.567

0.459

 Liver disease

15 (1)

21 (2)

0.503

32 (5)

26 (6)

0.492

< 0.0001

 Lung disease

7 (1)

7 (1)

1.000

7 (1)

9 (2)

0.205

0.018

Baseline assessments systolic

 Systolic BP, mmHg

123 [110, 140]

124 [110, 140]

0.653

125 [112, 140]

129 [110, 140]

0.829

0.193

 Diastolic BP, mmHg

79 [70, 89]

79 [70, 90]

0.586

80 [70, 90]

80 [70, 90]

0.713

0.642

 Heart rate, bpm

80 [70, 88]

85 [74, 98]

< 0.0001

84 [75, 95]

92 [80, 103]

< 0.0001

< 0.0001

Laboratory values

 Haemoglobin, g/L

145 [134, 156]

149 [137, 159]

0.000

142 [128, 155]

143 [129, 155]

0.628

< 0.0001

 Procalcitonin, ng/mL

0.05 [0.03, 0.09]

0.06 [0.04, 0.12]

< 0.0001

0.06 [0.04, 0.13]

0.07 [0.04, 0.20]

0.001

< 0.0001

 C-reactive protein, mg/L

5.48 [1.51, 19.87]

11.35 [3.30, 35.29]

< 0.0001

9.94 [2.21, 31.01]

17.84 [4.79, 52.54]

< 0.0001

0.000

  eGFR, mL/min/1.73 m2

104.37 [82.04, 129.46]

102.92 [78.87, 130.34]

0.175

94.46 [72.67, 123.28]

93.39 [63.49, 119.96]

0.118

< 0.0001

 Total cholesterol, mmol/L

1.33 [1.01, 1.86]

1.25 [0.92, 1.77]

< 0.0001

1.40 [1.07, 2.01]

1.61 [1.16, 2.27]

< 0.0001

0.800

 Triglyceride, mmol/L

3.81 [3.24, 4.45]

4.16 [3.48, 4.76]

0.000

3.83 [3.16, 4.54]

4.16 [3.44, 4.92]

0.001

< 0.0001

 HDL cholesterol, mmol/L

2.46 [2.00, 3.01]

2.76 [2.22, 3.32]

< 0.0001

2.47 [1.92, 3.10]

2.67 [2.16, 3.34]

0.037

< 0.0001

 LDL cholesterol, mmol/L

0.88 [0.75, 1.03]

0.97 [0.82, 1.15]

< 0.0001

0.86 [0.70, 1.03]

0.89 [0.73, 1.07]

0.000

0.357

 Apolipoprotein A, g/L

1.00 [0.88, 1.15]

1.04 [0.91, 1.18]

0.000

0.98 [0.84, 1.13]

1.01 [0.86, 1.18]

0.018

0.021

 Uric acid, μmol/L

311 [253, 384]

323 [264, 395]

0.002

319 [255.600, 397.500]

304 [232, 399]

0.061

0.004

 Peak hs Troponin I, ng/mL

4.75 [0.51, 21.73]

14.75 [2.66, 42.24]

< 0.0001

5.09 [0.92, 20.43]

10.45 [1.56, 34.57]

< 0.0001

0.007

Revascularization

 PCI

584 (54)

683 (58)

0.038

325 (51)

210 (49)

0.574

0.003

 CABG

4 (0)

2 (0)

0.436

1 (0)

1 (0)

1.00

1.000

Medications

 Statin

1076 (99)

1148 (97)

0.037

625 (98)

414 (97)

0.266

1.000

 Platelet inhibitor

1074 (98)

1159 (98)

0.869

626 (99)

420 (99)

0.792

0.648

 ACE inhibitor/ARB

771 (71)

783 (66)

0.030

470 (74)

294 (69)

0.094

0.307

 Beta-blocker

883 (81)

916 (78)

0.062

510 (80)

337 (79)

0.696

0.538

  1. Continuous variables are presented as median (IQR) while categorical ones as n (%)
  2. BMI body max index, LVEF left ventricular ejection fraction, STEMI ST-segment elevation myocardial infarction, CAD coronary artery disease, COPD chronic obstructive pulmonary disease, SBP systolic blood pressure, DBP diastolic blood pressure, eGFR estimated glomerular filtration rate, LAD left anterior descending coronary, LCX left circumflex artery, RCA right coronary artery, PCI percutaneous coronary intervention, CABG coronary artery bypass grafting, ACEI angiotensin-converting enzyme inhibitor, ARB angiotensin-receptor blocker
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Cardiovascular Diabetology

ISSN: 1475-2840