Fig. 4

Forest plot and non-linear dose–response curve (C) for association between TyG and CVD in general population, analyzed as category variables (highest vs. lowest) (A) or continuous variables (per 1-unit increasement) (B). In the forest plot, the diamond indicates the pooled estimate. Red boxes are relative to study size and the black vertical lines indicate 95% CIs around the effect size estimate. The dose–response association were fitted by using restricted cubic spline regression model. The bold lines indicate the pooled restricted cubic spline model and the black dashed line indicates the 95% CIs of the pooled curve. TyG: Triglyceride-glucose; CVD: cardiovascular disease