Skip to main content

Table 3 Unadjusted and multivariate cox regression analyses for all-cause mortality

From: Impact of red cell distribution width and red cell distribution width/albumin ratio on all-cause mortality in patients with type 2 diabetes and foot ulcers: a retrospective cohort study

 

Unadjusted HR (95% CI)

P-value

Adjusted HR (95% CI)

P-value

Total

 High RDW (vs. Low RDW)

2.802 (1.985–3.957)

 < 0.001

2.426 (1.557–3.778) a

 < 0.001

 High RDW/ALB (vs. Low RDW/ALB)

2.993 (2.031–4.410)

 < 0.001

2.360 (1.414–3.942) b

0.001

No severe DFUs

 High RDW (vs. Low RDW)

2.780 (1.538–5.023)

0.001

2.893 (1.387–6.036) c

0.005

 High RDW/ALB (vs. Low RDW/ALB)

3.766 (2.006–7.070)

 < 0.001

3.086 (1.343–7.093) d

0.008

Severe DFUs

 High RDW (vs. Low RDW)

2.787 (1.820–4.267)

 < 0.001

2.539 (1.412–4.563) c

0.002

 High RDW/ALB (vs. Low RDW/ALB)

2.259 (1.380–3.698)

0.001

1.973 (1.026–3.796) d

0.042

No severe PAD

 High RDW (vs. Low RDW)

3.940 (1.669–9.305)

0.002

4.055 (1.397–11.767) e

0.010

 High RDW/ALB (vs. Low RDW/ALB)

9.754 (2.286–41.614)

0.002

11.585 (1.378–97.397) f

0.024

Severe PAD

 High RDW (vs. Low RDW)

2.240 (1.456–3.446)

 < 0.001

2.461 (1.474–4.107) e

0.001

 High RDW/ALB (vs. Low RDW/ALB)

2.339 (1.500–3.649)

 < 0.001

2.028 (1.187–3.463) f

0.010

Age < 65

 High RDW (vs. Low RDW)

2.089 (0.693–6.295)

0.191

2.855 (0.678–12.015) a

0.153

 High RDW/ALB (vs. Low RDW/ALB)

17.645 (2.362–131.837)

0.005

11.217 (1.369–91.925) b

0.024

Age ≥ 65

 High RDW (vs. Low RDW)

2.597 (1.801–3.745)

 < 0.001

2.758 (1.680–4.525) a

 < 0.001

 High RDW/ALB (vs. Low RDW/ALB)

2.485 (1.664–3.711)

 < 0.001

1.959 (1.143–3.357) b

0.014

  1. aThe multivariable cox regression was adjusted for risk factors including age, BMI, SBP, severe DFUs, severe PAD, Hb, ALB, eGFR, cerebrovascular disease, diabetic retinopathy, diabetic peripheral neuropathy
  2. bThe multivariable cox regression was adjusted for risk factors including age, BMI, SBP, severe DFUs, severe PAD, Hb, eGFR, cerebrovascular disease, diabetic retinopathy, diabetic peripheral neuropathy
  3. cThe multivariable cox regression was adjusted for risk factors including age, BMI, SBP, severe PAD, Hb,ALB, eGFR, cerebrovascular disease, diabetic retinopathy, diabetic peripheral neuropathy
  4. dThe multivariable cox regression was adjusted for risk factors including age, BMI, SBP, severe PAD, Hb, eGFR, cerebrovascular disease, diabetic retinopathy, diabetic peripheral neuropathy
  5. eThe multivariable cox regression was adjusted for risk factors including age, BMI, SBP, severe DFUs, Hb,ALB, eGFR, cerebrovascular disease, diabetic retinopathy, diabetic peripheral neuropathy
  6. fThe multivariable cox regression was adjusted for risk factors including age, BMI, SBP, severe DFUs, Hb, eGFR, cerebrovascular disease, diabetic retinopathy, diabetic peripheral neuropathy. In subgroup analyses, all P-value for interactions > 0.05
  7. RDW red cell distribution width, ALB albumin, BMI body mass index, DFUs diabetic foot ulcers, PAD peripheral artery disease, SBP systolic blood pressure, eGFR estimated glomerular filtration rate, Hb hemoglobin. Results with P value <0.05 were emphasized using bold letters.
Back to article page

Cardiovascular Diabetology

ISSN: 1475-2840