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Table 1 Baseline characteristics of the study population

From: Impact of type 2 diabetes mellitus on left ventricular deformation in non-ischemic dilated cardiomyopathy patients assessed by cardiac magnetic resonance imaging

 

Normal controls (n = 80)

NIDCM (T2DM −) (n = 342)

NIDCM (T2DM +) (n = 93)

Age (years)

47.03 ± 12.09

48.89 ± 14.53

55.80 ± 12.07 *, §

Male, n (%)

55 (69)

233 (68)

71 (76)

Systolic BP (mm Hg)

113.59 ± 18.26

113.68 ± 17.87

117.37 ± 20.63

Diastolic BP (mm Hg)

76.38 ± 14.44

74.99 ± 14.84

76.98 ± 13.56

Heart rate (beats/min)

74.15 (65.20, 80.43)

76.00 (66.55, 88.43)

81.75 ± 15.03

BMI (kg/m2)

24.05 ± 3.66

23.86 ± 4.78

24.67 ± 3.63

Smoking, n (%)

36 (45)

183 (54)

46 (49)

NYHA class

   

(I/II/III/IV)

11/85/161/85

2/19/45/27

Diabetes duration (years)

4.00 (0.30, 10.00)

Fasting blood glucose (mmol/L)

5.47 ± 1.29

7.82 (6.12, 10.71) §

HbA1c, (%)

5.60 ± 0.54

7.40 (6.80, 8.50) §

TG (mmol/L)

1.41 ± 0.42

1.29 (0.92, 1.81)

1.45 (1.00, 2.04)

TC (mmol/L)

4.33 ± 0.61

4.12 (3.48, 4.86)

4.26 ± 1.11

HDL (mmol/L)

1.43 ± 0.32

1.11 (0.84, 1.41)

1.09 ± 0.34

LDL (mmol/L)

2.54 ± 0.62

2.51 (1.95, 2.98)

2.56 ± 0.86

eGFR (mL/min/1.73 m2)

100.01 (92.00, 108.24)

88.61 (74.72, 100.47) *

81.85 ± 21.82 *

NT-proBNP value (pg/mL)

1448.00 (628.75, 3402.00)

2473.00 (960.50, 5956.50) §

Troponin T value (ng/L)

15.65 (9.88, 29.33)

25.00 (15.60, 44.90) §

Medical treatment (for DCM), n (%)

ACEI/ARB

315 (92)

87 (94)

β‐blocker

325 (95)

87 (94)

MRA

257 (75)

64 (69)

Diuretics

212 (62)

62 (67)

Digoxin

79 (23)

20 (22)

Diabetes treatment, n (%)

Biguanides

32 (34)

Sulfonylureas

17 (18)

a‐Glucosidase inhibitor

29 (31)

GLP‐1/DPP‐4 inhibitor

4 (4)

SGLT2 inhibitor

10 (11)

Insulin

23 (25)

  1. All values are presented as mean ± SD or n (%) or median (Q1-Q3)
  2. NIDCM non-ischemic dilated cardiomyopathy, T2DM type 2 diabetes diabetes mellitus, BMI body mass index, NYHA New York Heart Association, HbA1c glycated hemoglobin, TG triglycerides, TC total cholesterol, HDL high-density lipoprotein, LDL low-density lipoprotein, eGFR estimated Glomerular Filtration Rate, NT-proBNP N-terminal pro-brain natriuretic peptide, ACEI angiotensin-converting enzyme inhibitor, ARB angiotensin receptor blocker, MRA mineralocorticoid receptor antagonist, GLP-1 glucagon-like peptide-1, DPP-4 dipeptidyl peptidase-4, SGLT2 sodium-glucose co-transporter 2
  3. *P < 0.017 vs. normal controls; §P < 0.017 vs. NIDCM (T2DM −) group