| Event N (%) | Model 1 | Model 2 | Model 3 |
---|---|---|---|---|
(A) MACEs | ||||
 Q1 | 2342/90,654 (2.58) | Reference | Reference | Reference |
 Q2 | 2951/90,798 (3.25) | 1.259 (1.192–1.329) | 1.174 (1.112–1.240) | 1.113 (1.054–1.175) |
 Q3 | 3262/90,672 (3.60) | 1.395 (1.323–1.471) | 1.296 (1.229–1.367) | 1.175 (1.113–1.240) |
 Q4 | 3578/90,739 (3.96) | 1.533 (1.455–1.615) | 1.503 (1.427–1.584) | 1.278 (1.209–1.350) |
(B) CV events | ||||
 Q1 | 2123/90,654 (2.34) | Reference | Reference | Reference |
 Q2 | 2677/90,798 (2.36) | 1.260 (1.190–1.334) | 1.178 (1.113–1.248) | 1.115 (1.053–1.181) |
 Q3 | 2984/90,672 (2.96) | 1.408 (1.332–1.489) | 1.311 (1.240–1.386) | 1.185 (1.120–1.255) |
 Q4 | 3271/90,739 (3.28) | 1.546 (1.464–1.633) | 1.515 (1.434–1.600) | 1.284 (1.212–1.360) |
(C) CV mortality | ||||
 Q1 | 428/90,654 (0.47) | Reference | Reference | Reference |
 Q2 | 491/90,798 (0.48) | 1.142 (1.003–1.299) | 1.044 (0.917–1.188) | 1.008 (0.885–1.149) |
 Q3 | 509/90,672 (0.56) | 1.184 (1.042–1.347) | 1.094 (0.962–1.244) | 1.014 (0.889–1.157) |
 Q4 | 514/90,739 (0.56) | 1.196 (1.052–1.360) | 1.222 (1.075–1.390) | 1.062 (0.928–1.215) |