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Table 7 Targets for lipid control

From: Cardiovascular disease in type 2 diabetes mellitus: progress toward personalized management

Parameter Target Population Guideline References
Lipid LDL-C Reduction of ≥ 50% or more from baseline Adults with diabetes and 10 year atherosclerotic CVD risk of 20% or higher ADA [91]
LDL-C Reduction of ≥ 50% from baseline Patients with DM and atherosclerotic CVD AHA [39]
LDL-C Reduction of ≥ 50% from baseline and < 70 mg/dL Patients with T2DM > 40 years of age at high CVD risk ESC [41]
LDL-C Reduction of ≥ 50% from baseline and < 55 mg/dL Patients with T2DM at very high CVD risk
LDL-C  < 100 mg/dL Patients with T2DM at moderate CV risk ESC/EASD [94]
 < 70 mg/dL Patients with T2DM at high CV risk
 < 55 mg/dL Patients with T2DM at very high CV risk
  1. CV cardiovascular, ASCVD atherosclerotic cardiovascular disease, ADA American Diabetes Association, ESC European Society of Cardiology, EASD European Association for the Study of Diabetes, AHA American Heart Association, LDL-C low-density lipoprotein cholesterol, HDL-C high-density lipoprotein cholesterol, DM diabetes mellitus