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Table 7 Targets for lipid control

From: Cardiovascular disease in type 2 diabetes mellitus: progress toward personalized management

Parameter

Target

Population

Guideline

References

Lipid

LDL-C

Reduction of ≥ 50% or more from baseline

Adults with diabetes and 10 year atherosclerotic CVD risk of 20% or higher

ADA

[91]

LDL-C

Reduction of ≥ 50% from baseline

Patients with DM and atherosclerotic CVD

AHA

[39]

LDL-C

Reduction of ≥ 50% from baseline and < 70 mg/dL

Patients with T2DM > 40 years of age at high CVD risk

ESC

[41]

LDL-C Reduction of ≥ 50% from baseline and < 55 mg/dL

Patients with T2DM at very high CVD risk

LDL-C

 < 100 mg/dL

Patients with T2DM at moderate CV risk

ESC/EASD

[94]

 < 70 mg/dL

Patients with T2DM at high CV risk

 < 55 mg/dL

Patients with T2DM at very high CV risk

  1. CV cardiovascular, ASCVD atherosclerotic cardiovascular disease, ADA American Diabetes Association, ESC European Society of Cardiology, EASD European Association for the Study of Diabetes, AHA American Heart Association, LDL-C low-density lipoprotein cholesterol, HDL-C high-density lipoprotein cholesterol, DM diabetes mellitus