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Table 3 Association of cumulative TyG index with ischemic stroke

From: Relationship of cumulative exposure to the triglyceride-glucose index with ischemic stroke: a 9-year prospective study in the Kailuan cohort

 

Case/ Total

Incidence rate, per 1000 person-years

Model 1

Model 2

Model 3

Quartiles

 Q1

312/13524

2.56

1.00

1.00

1.00

 Q2

435/13525

3.66

1.24 (1.07,1.44)

1.14 (0.98,1.32)

1.09 (0.94,1.27)

 Q3

604/13525

5.24

1.53 (1.33,1.76)

1.34 (1.17,1.55)

1.26 (1.09,1.45)

 Q4

732/13524

6.68

1.79 (1.56,2.05)

1.45 (1.25,1.67)

1.30 (1.12,1.52)

 P for Trend

  

 < 0.0001

 < 0.0001

0.0002

Time exposure duration

  

 0 year

365/14630

2.89

1.00

1.00

1.00

 2 years

415/12653

3.79

1.37 (1.19,1.57)

1.22 (1.06,1.40)

1.18 (1.02,1.36)

 4 years

501/11733

4.95

1.77 (1.54,2.02)

1.42 (1.23,1.63)

1.32 (1.14,1.54)

 6 years

802/15082

6.26

2.18 (1.92,2.47)

1.57 (1.37,1.80)

1.38 (1.16,1.64)

 P for Trend

  

 < 0.0001

 < 0.0001

0.0003

  1. Model 1 age (continuous variable, years) and sex (categorical variable, men or women)
  2. Model2: included variables in model 1 and further LDL-C (continuous variable, mmol/L), HDL-C (continuous variable, mmol/L), BMI (continuous variable, kg/m2), hs-CRP (continuous variable, mg/L), smoking status (categorical variable, smoker or non-smoker), alcohol consumption habits (categorical variable, drinker or non-drinker), physical exercise habits (categorical variable, active or inactive), hypertension (categorical variable, yes or no), diabetes mellitus (categorical variable, yes or no), and the use of lipid-lowering drugs (categorical variable, yes or no)
  3. Model 3: included variables in model 2 and further the TyG index (continuous variable) at baseline