| |
Case/ Total
|
Incidence rate, per 1000 person-years
|
Model 1
|
Model 2
|
Model 3
|
|---|
|
Quartiles
|
|
Q1
|
312/13524
|
2.56
|
1.00
|
1.00
|
1.00
|
|
Q2
|
435/13525
|
3.66
|
1.24 (1.07,1.44)
|
1.14 (0.98,1.32)
|
1.09 (0.94,1.27)
|
|
Q3
|
604/13525
|
5.24
|
1.53 (1.33,1.76)
|
1.34 (1.17,1.55)
|
1.26 (1.09,1.45)
|
|
Q4
|
732/13524
|
6.68
|
1.79 (1.56,2.05)
|
1.45 (1.25,1.67)
|
1.30 (1.12,1.52)
|
|
P for Trend
| | |
< 0.0001
|
< 0.0001
|
0.0002
|
|
Time exposure duration
| | |
|
0 year
|
365/14630
|
2.89
|
1.00
|
1.00
|
1.00
|
|
2 years
|
415/12653
|
3.79
|
1.37 (1.19,1.57)
|
1.22 (1.06,1.40)
|
1.18 (1.02,1.36)
|
|
4 years
|
501/11733
|
4.95
|
1.77 (1.54,2.02)
|
1.42 (1.23,1.63)
|
1.32 (1.14,1.54)
|
|
6 years
|
802/15082
|
6.26
|
2.18 (1.92,2.47)
|
1.57 (1.37,1.80)
|
1.38 (1.16,1.64)
|
|
P for Trend
| | |
< 0.0001
|
< 0.0001
|
0.0003
|
- Model 1 age (continuous variable, years) and sex (categorical variable, men or women)
- Model2: included variables in model 1 and further LDL-C (continuous variable, mmol/L), HDL-C (continuous variable, mmol/L), BMI (continuous variable, kg/m2), hs-CRP (continuous variable, mg/L), smoking status (categorical variable, smoker or non-smoker), alcohol consumption habits (categorical variable, drinker or non-drinker), physical exercise habits (categorical variable, active or inactive), hypertension (categorical variable, yes or no), diabetes mellitus (categorical variable, yes or no), and the use of lipid-lowering drugs (categorical variable, yes or no)
- Model 3: included variables in model 2 and further the TyG index (continuous variable) at baseline
