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Table 3 Percentages of patients with insulin resistance indexes above (for HOMA-IR, I0/G0, I2/G2) or below (for QUICKI) the respective cut-off values

From: Prediabetes and insulin resistance in a population of patients with heart failure and reduced or preserved ejection fraction but without diabetes, overweight or hypertension

Index

Cut-off Value

HF groups

p

Control group (%)

p*

Total HF (%)

HFrEF (%)

HFpEF (%)

HOMA-IR

2.53

55.3

58.8

50.0

0.236

26.3

< 0.0001

I0/G0

3.81

30.0

31.6

27.6

0.563

13.7

0.008

I2/G2

14.54

28.9

30.7

26.3

0.516

17.9

0.103

QUICKI

0.33

56.3

60.5

50.0

0.153

30.5

< 0.0001

  1. HOMA-IR homeostatic model assessment of insulin resistance; I0/G0 plasma insulin/glucose ratio measured at fasting; I2/G2 plasma insulin/glucose ratio measured 2 h after glucose intake; QUICKI quantitative insulin-sensitivity check index
  2. p: comparisons between HFrEF and HFpEF groups
  3. p*: comparisons between the total HF group and the control group