Skip to main content

Table 1 Baseline Clinical Characteristics by TyG Group

From: Prognostic value of triglyceride glucose (TyG) index in patients with acute decompensated heart failure

Characteristic

Total

Tertile I (Lowest)

(n = 310)

TyG < 8.83

Tertile II (Median)

(n = 309)

8.83 ≤ TyG < 9.32

Tertile III (Highest)

(n = 313)

TyG ≥ 9.32

p Value

Female, n (%)

353(37.9)

95(26.9)

133(37.7)

125(35.4)

 < 0.001

##

Age (years)

70(61,80)

73(64,82)

71(63,79)

67(56,76)

 < 0.001

#,***,&&

BMI (kg/m2)

24.2(21.6,27.1)

23.3(20.5,26.1)

24.1(21.5,26.5)

25.2(22.7,28.1)

 < 0.001

#,***,&&

Heart Rate (bpm)

81(70,97)

80(68,95)

81(70,97)

84(71,98)

0.261

 

SBP (mmHg)

129(114,145)

127(114,147)

128(113,142)

130(116,144)

0.456

 

DBP (mmHg)

75(66,87)

75(65,85)

75(66,87)

76(67,87)

0.507

 

Medical history, n (%)

      

 Ischemic cardiomyopathy

347(37.2)

105(33.9)

99(32)

143(45.7)

0.001

*,&&

 None-ischemic cardiomyopathy

197(21.1)

53(17.1)

74(23.9)

70(22.4)

0.091

 

 Valvular heart disease

174(18.7)

70(22.6)

60(19.4)

44(14.1)

0.022

*

 Atrial fibrillation

404(43.3)

169(54.5)

139(45.0)

96(30.7)

 < 0.001

***,&&&

 Hypertension

563(60.4)

172(55.5)

186(60.2)

205(65.5)

0.038

*

 Hyperlipidemia

72(43.3)

5(1.6)

20(6.5)

47(15.0)

 < 0.001

#,***,&&

 Diabetes mellitus

306(32.8)

64(20.6)

83(26.9)

159(50.8)

 < 0.001

***,&&&

Anemia

429(46.0)

177(57.3)

134(44.1)

118(37.9)

 < 0.001

##,*

Hemoglobin(g/L)

128.0(110.1,142.4)

125.0(107.6,138.1)

129.5(111.3,141.8)

132.0(114.0,145.0)

 < 0.001

***

FPG (mg/dL)

91.8(81.9,112.0)

82.6(75.6,91.1)

92.2(83.9,104.9)

118.44(92.2,151.7)

 < 0.001

###,***,&&&

HbA1c (%)

6.1(5.6,7.0)

6.0(5.6,6.4)

6.1(5.6,6.8)

6.8(5.8,7.9)

 < 0.001

***,&&&

BNP (pg/mL)

589.5(307.8,1230.0)

591.5(339.3,1167.5)

606(123.5,1088.5)

552.0(177.3,926.8)

0.476

 

CRP (mg/L)

4.5(2.9,12.4))

4.4(2.9,9.3)

4.6(3.0,14.7)

4.4(3.0,14.5)

0.330

 

Hematocrit (%)

38.4(33.8,42.2)

37.3(33.1,41.1)

38.7(34.1,42.1)

39.10(35.1,43.2)

0.001

***

ALB (g/L)

38.2(35.4,40.5)

37.4(35.1,39.2)

38.4(36.0,40.8)

39.1(35.5,41.4)

 < 0.001

#,***

UA (μmol/L)

439.0(343.25,550.75)

419.5(328.3,528.3)

430.0(325.0,558.5)

448(372.5,555.0)

0.033

*

Creatinine (μmol/L)

84.3(67.0,113.0)

84.4(69.1,107.1)

87.0(65.3,113.0)

85.10(65.7,119.8)

0.971

 

Sodium (mmol/L)

138.3(135.5,141.5)

138.3(135.4,141.4)

139.0(135.8,141.8)

138.2(135.2,141.2)

0.458

 

Potassium (mmol/L)

3.9(3.6,4.2)

3.9(3.5,4.2)

3.9(3.6,4.2)

3.90(3.6,4.3)

0.707

 

WBC (10^9/L)

6.2(5.0,7.8)

5.5(4.5,6.9)

6.1(5.1,7.7)

6.95(5.7,8.7)

 < 0.001

###,***,&&&

RDW (%)

13.7(12.9,13.7)

14.1(13.2,15.1)

13.6(12.9,14.7)

13.4(12.8,14.3)

 < 0.001

***,&

Total cholesterol (mg/dL)

138.16(114.07,170.15)

120.36(103.93,145.11)

141.26(118.71,168.60)

156.74(129.93,188.90)

 < 0.001

###,***,&&&

Triglyceride (mg/dL)

90.27(29.00,54.91)

61.07(22.43,30.55)

92.04(35.19,46.40)

149.57(50.08,83.91)

 < 0.001

###,***,&&&

HDL-C (mg/dL)

37.15(29.78,46.79)

40.25(33.06,50.46)

38.70(30.55,49.50)

33.28(27.07,40.60)

 < 0.001

###,***

LDL-C (mg/dL)

77.79(58.05,101.32)

65.79(50.46,82.75)

79.72(60.71,103.25)

89.78(65.74,116.01)

 < 0.001

###,***,&&

AST (U/L)

23.0(17.3,33.6)

23.1(17.5,32.8)

24.0(17.5,33.0)

21.60(17.1,35.4)

0.568

 

ALT (U/L)

19.4(12.9,32.5)

18.6(11.9,28.2)

19.5(13.1,31.9)

20.60(14.1,38.9)

0.027

 

IVSTD (cm)

0.9(0.8,1.0)

0.9(0.8,1.0)

0.90(0.8,1.0)

0.90(0.8,1.1)

0.357

 

LVPWTD (cm)

0.9(0.8,1.0)

0.90(0.8,1.0)

0.90(0.8,1.0)

0.90(0.8,1.0)

0.173

 

LVDD (cm)

5.9(5.2,6.5)

5.8(5.1,6.5)

5.9(5.2,6.5)

5.9(5.2,6.7)

0.270

 

LAD (cm)

4.8(4.4,5.3)

5.0(4.5,5.5)

4.8(4.5,5.3)

4.7(4.2,5.2)

 < 0.001

#,***,&

LVEF, n (%)

    

0.048

*

 ≤ 40%

493(52.9)

144(46.5)

168(54.4)

181(57.8)

-

 

41% ~ 49%

154(16.5)

63(20.3)

46(14.9)

45(14.4)

-

 

 ≤  50%

285(30.6)

103(33.2)

95(30.7)

87(27.8)

-

 

Medications at admission,

n (%)

      

Antiplatelet agent

412(44.2)

116(37.4)

135(43.7)

161(51.4)

0.002

**

ACEI/ARB/ARNI

150(16.1)

52(16.8)

43(13.9)

55(17.6)

0.428

 

Beta-blocker

726(77.9)

236(76.1)

242(78.3)

248(79.2)

0.633

 

Statins

509(54.6)

154(49.7)

164(53.1)

191(61.0)

0.014

*

Diuretics

819(87.9)

270(87.1)

281(90.9)

268(53.7)

0.103

 

Loop

810(86.9)

268(86.5)

279(90.0)

263(84.0)

0.072

 

Thiazide

51(5.5)

19(6.1)

15(4.9)

17(5.4)

0.784

 

Digoxin

102(10.9)

38(12.3)

24(7.8)

40(12.8)

0.079

 

Aldosterone antagonist

375(40.2)

128(41.3)

128(41.4)

119(38.0)

0.616

 

Insulin

211(22.6)

41(13.2)

58(18.8)

112(35.8)

 < 0.001

**&&

Metformin

106(11.4)

15(4.8)

32(10.4)

59(18.8)

 < 0.001

##,***&&

Sulfonylureas

4(0.4)

1(0.1)

1(0.1)

2(0.2)

0.785

 

SGLT2i

27(2.9)

5(1.6)

5(1.6)

17(1.8)

0.005

**,&&

Other hypoglycemic drugs

172(18.5)

34(3.6)

43(4.6)

95(10.2)

 < 0.001

***,&&

  1. BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, FPG fasting plasma glucose, BNP B-type natriuretic peptide, CRP C-creative protein, ALB albumin, UA uric acid, Cr creatinine; Na sodium; K potassium, WBC white blood cell, RDW red blood cell distribution width, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein-C, AST alanine aminotransferase, ALT aspartate transaminase; IVSTD interventricular septal thickness at diastole, LVPWTD left ventricular posterior wall end-diastolic thickness, LVDD left ventricular end-diastolic diameter, LAD left atrial diameter, LVEF left ventricular ejection fraction, ACEI angiotensin-converting enzyme inhibitor, ARB angiotensin receptor inhibitor, ARNI angiotensin receptor neprilysin inhibitor, SGLT2i Sodium-glucose cotransporter 2 inhibitor
  2. #P < 0.05, ##P < 0.01, ### P < 0.001: T1 group vs T2 group
  3. *P < 0.05, **P < 0.01, *** P < 0.001: T1 group vs T3 group
  4. &P < 0.05, &&P < 0.01, &&& P < 0.001: T2 group vs T3 group
Back to article page

Cardiovascular Diabetology

ISSN: 1475-2840