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Fig. 1 | Cardiovascular Diabetology

Fig. 1

From: Time trends (2001–2019) and sex differences in incidence and in-hospital mortality after lower extremity amputations among patients with type 1 diabetes in Spain

Fig. 1

Joinpoint analysis of annual LEAS in patients with type 1 diabetes in Spain. A Joinpoint analysis of annual minor LEAs in women with T1DM in Spain, 2001–2019. B Joinpoint analysis of annual minor LEAs in men with T1DM in Spain, 2001–2019. C Joinpoint analysis of annual major LEAs in patients with T1DM in Spain, 2001–2019. D Joinpoint analysis of annual major LEAs in women with T1DM in Spain, 2001–2019. E Joinpoint analysis of annual major LEAs in men with T1DM in Spain, 2001–2019. APC: Annual percent change (based on rates that were sex and aged-adjusted using the Spanish National Statistics Institute Census projections) calculated using joinpoint regression analysis. ˆAPC is significantly different from zero (two-side P < 0.05)

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