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Table 1 Baseline clinical and demographic characteristics and comorbidities in the CorLipid population by the presence of coronary syndrome

From: Prognostic significance of metabolomic biomarkers in patients with diabetes mellitus and coronary artery disease

 

All diabetic patients

(n = 316)

Diabetic patients with ACS

(N = 176)

Diabetic patients with CCS

(N = 140)

P-value

Clinical characteristics, No. (%)

    

 Male gender

222 (70.3)

129 (73.3)

93(66.4)

0.18

 STEMI

62 (19.6)

62 (35.2)

0 (0)

–

 NSTEMI

59 (18.7)

59 (33.5)

0 (0)

–

 Unstable angina

55 (17.4)

55 (31.3)

0 (0)

–

 Smoking

129 (40.8)

87 (49.4)

42 (30)

< 0.01

Clinical parameters [mean (± SD) /

Median (IQR = Q3-Q1)*]

    

 Age (years)

67 (11)

66 (13)

67 (10)

0.60

 Body mass index (kg/m2)

29.4 (5.1)

28.8(4.9)

29.3 (5)

0.40

 Estimated glomerular filtration rate by CKD-EPI (mL/min/1.73m2)

90 (39.3)

89 (40.7)

92.3 (36.9)

0.46

 Left ventricular ejection fraction (%)

50 (10)

50 (11)

55 (9)

< 0.01

 Total cholesterol (mg/dL)

155 (44)

156 (45)

155 (45)

0.86

 Triglycerides (mg/dL)*

130 (1656)

130 (1656)

128 (1563)

0.90

 High density lipoprotein (mg/dL)

41 (12)

40 (12)

44 (14)

0.02

 Low density lipoprotein (mg/dL)

82 (36)

85 (38)

82 (35)

0.43

 Fasting glucose (mg/dL)*

127 (416)

128 (399)

126 (380)

0.62

 Glycated hemoglobin A1c (%)

7.3 (1.6)

7.1 (1)

7.2 (1.4)

0.34

 Peak high-sensitivity cardiac troponin (ng/L)*

35(9996)

207(9996)

15(1582)

< 0.01

Medical histories, No. (%)

    

 Hypertension

237 (75)

127 (72.2)

110 (78.6)

0.19

 Dyslipidemia

155 (49.1)

80(45.5)

75 (53.6)

0.15

 Heart failure

9 (2.8)

7 (11.4)

2 (4.3)

0.17

 Chronic kidney disease

26 (8.2)

20 (4.6)

6 (2.9)

0.02

 Peripheral vascular disease

22 (7)

12 (6.8)

10 (7.1)

0.91

 Atrial fibrillation

32 (10.1)

18 (10.2)

14 (10)

0.94

 Prior stroke

12 (3.8)

5 (2.8)

7 (5)

0.31

 Positive family history of CAD

47 (14.9)

29 (16.6)

18 (12.9)

0.35

 Statin medication

185 (58.5)

97 (55.1)

88 (63.8)

0.12

 Oral anticoagulant medication

45 (14.2)

31 (17.6)

14 (10.1)

0.061

  1. Variables with p value < 0.05 were identified as significant variables and they are in bold
  2. *Mean values and standard deviations are provided for variables with normal distribution, while median values and interquartile range (IQR) are provided for variables with non-normal distribution