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Table 1 Baseline clinical and demographic characteristics and comorbidities in the CorLipid population by the presence of coronary syndrome

From: Prognostic significance of metabolomic biomarkers in patients with diabetes mellitus and coronary artery disease

  All diabetic patients
(n = 316)
Diabetic patients with ACS
(N = 176)
Diabetic patients with CCS
(N = 140)
P-value
Clinical characteristics, No. (%)     
 Male gender 222 (70.3) 129 (73.3) 93(66.4) 0.18
 STEMI 62 (19.6) 62 (35.2) 0 (0)
 NSTEMI 59 (18.7) 59 (33.5) 0 (0)
 Unstable angina 55 (17.4) 55 (31.3) 0 (0)
 Smoking 129 (40.8) 87 (49.4) 42 (30) < 0.01
Clinical parameters [mean (± SD) /
Median (IQR = Q3-Q1)*]
    
 Age (years) 67 (11) 66 (13) 67 (10) 0.60
 Body mass index (kg/m2) 29.4 (5.1) 28.8(4.9) 29.3 (5) 0.40
 Estimated glomerular filtration rate by CKD-EPI (mL/min/1.73m2) 90 (39.3) 89 (40.7) 92.3 (36.9) 0.46
 Left ventricular ejection fraction (%) 50 (10) 50 (11) 55 (9) < 0.01
 Total cholesterol (mg/dL) 155 (44) 156 (45) 155 (45) 0.86
 Triglycerides (mg/dL)* 130 (1656) 130 (1656) 128 (1563) 0.90
 High density lipoprotein (mg/dL) 41 (12) 40 (12) 44 (14) 0.02
 Low density lipoprotein (mg/dL) 82 (36) 85 (38) 82 (35) 0.43
 Fasting glucose (mg/dL)* 127 (416) 128 (399) 126 (380) 0.62
 Glycated hemoglobin A1c (%) 7.3 (1.6) 7.1 (1) 7.2 (1.4) 0.34
 Peak high-sensitivity cardiac troponin (ng/L)* 35(9996) 207(9996) 15(1582) < 0.01
Medical histories, No. (%)     
 Hypertension 237 (75) 127 (72.2) 110 (78.6) 0.19
 Dyslipidemia 155 (49.1) 80(45.5) 75 (53.6) 0.15
 Heart failure 9 (2.8) 7 (11.4) 2 (4.3) 0.17
 Chronic kidney disease 26 (8.2) 20 (4.6) 6 (2.9) 0.02
 Peripheral vascular disease 22 (7) 12 (6.8) 10 (7.1) 0.91
 Atrial fibrillation 32 (10.1) 18 (10.2) 14 (10) 0.94
 Prior stroke 12 (3.8) 5 (2.8) 7 (5) 0.31
 Positive family history of CAD 47 (14.9) 29 (16.6) 18 (12.9) 0.35
 Statin medication 185 (58.5) 97 (55.1) 88 (63.8) 0.12
 Oral anticoagulant medication 45 (14.2) 31 (17.6) 14 (10.1) 0.061
  1. Variables with p value < 0.05 were identified as significant variables and they are in bold
  2. *Mean values and standard deviations are provided for variables with normal distribution, while median values and interquartile range (IQR) are provided for variables with non-normal distribution