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Table 2 Characteristics of participants at baseline by the incidence of all-cause death during follow-up

From: Differential prognostic burden of cardiovascular disease and lower-limb amputation on the risk of all-cause death in people with long-standing type 1 diabetes

 

All-cause death

P

No

Yes

N

865

304

 

Cohort membership, n (%)

  

 < 0.0001

SURGENE

275 (32)

62 (20)

 

GENEDIAB

212 (25)

164 (54)

 

GENESIS

378 (44)

78 (26)

 

Male sex, n (%)

452 (52)

191 (63)

0.001

Age (years)

37 ± 11

49 ± 13

 < 0.0001

Age of diabetes onset (years)

14 (10, 22)

17 (12, 27)

 < 0.0001

Duration of diabetes (years)

21 ± 11

30 ± 10

 < 0.0001

Body mass index (kg/m2)

24 ± 3

24 ± 4

0.36

Tobacco smoking, n (%)

  

 < 0.0001

Former smokers

69 (8)

50 (16)

 

Current smokers

165 (19)

76 (25)

 

Systolic blood pressure (mmHg)

129 ± 18

141 ± 19

 < 0.0001

Diastolic blood pressure (mmHg)

75 ± 11

79 ± 11

 < 0.0001

HbA1c (%)

8.8 ± 1.8

8.8 ± 1.9

0.52

HbA1c (mmol/mol)

72 ± 20

73 ± 21

 

Total cholesterol (mmol/l)a

5.5 ± 1.4

5.9 ± 1.5

0.0003

eGFR (mL/min/1.73m2)

92 ± 27

70 ± 31

 < 0.0001

Urinary albumin concentration (mg/l)

11 (5, 51)

45 (8, 552)

 < 0.0001

Diabetic kidney disease, n (%)

299 (35)

185 (61)

 < 0.0001

Diabetic retinopathy stages, n (%)

  

 < 0.0001

Non-proliferative

242 (28)

34 (11)

 

Pre-proliferative

123 (14)

59 (19)

 

Proliferative

307 (35)

196 (64)

 

Peripheral diabetic neuropathy, n (%)

246 (28)

166 (55)

 < 0.0001

Peripheral artery disease, n (%)

16 (3)

55 (23)

 < 0.0001

Antihypertensive drugs, n (%)

283 (33)

186 (62)

 < 0.0001

Lipid-lowering drugs, n (%)

37 (4)

32 (10)

 < 0.0001

  1. Quantitative variables are presented as mean ± SD or as median (25th–75th percentiles) for those with skewed distribution (age of diabetes onset and urinary albumin concentration)
  2. Comparisons were performed using χ2, ANOVA or Wilcoxon tests
  3. P < 0.05 was considered as significant
  4. aData available for 664 participants