From: Bilirubin as an indicator of cardiometabolic health: a cross-sectional analysis in the UK Biobank
Baseline characteristic | Total bilirubin tertile | Total bilirubin tertile | ||||
---|---|---|---|---|---|---|
1 | 2 | 3 | 1 | 2 | 3 | |
Men | Women | |||||
n = 71,496 | n = 71,270 | n = 71,240 | n = 84,930 | n = 84,185 | n = 84,398 | |
Bilirubin levels (μmol/L)Ω | 6.7 [5.9; 7.4] | 9.1 [8.5; 9.8] | 13.2 [11.7; 16.5] | 5.4 [4.8; 5.9] | 7.3 [6.8; 7.8] | 10.4 [9.2; 12.8] |
Age (years)a | 56.6 (8.2) | 56.9 (8.1) | 56.8 (8.3) | 56.3 (7.9) | 56.8 (7.9) | 56.0 (8.2) |
Weight (kg)a | 86.3 (15.1) | 86.0 (14.1) | 85.5 (13.7) | 73.0 (14.7) | 71.3 (13.9) | 69.9 (13.3) |
Height (cm)a | 174.9 (6.8) | 175.8 (6.8) | 176.2 (6.9) | 161.8 (6.3) | 162.5 (6.3) | 163.1 (6.3) |
Body mass index (kg/m2)a | 28.2 (4.5) | 27.8 (4.1) | 27.5 (4.0) | 27.9 (5.4) | 27.0 (5.1) | 26.3 (4.9) |
Waist circumference (cm)a | 97.9 (11.8) | 96.8 (11.1) | 96.0 (10.9) | 86.7 (12.9) | 84.5 (12.3) | 82.8 (12.0) |
Hip circumference (cm)a | 103.6 (8.1) | 103.4 (7.5) | 103.2 (7.2) | 104.6 (10.9) | 103.3 (10.2) | 102.1 (9.8) |
Waist-hip ratioa | 0.9 (0.1) | 0.9 (0.1) | 0.9 (0.1) | 0.8 (0.1) | 0.8 (0.1) | 0.8 (0.1) |
Fat mass (kg)a | 22.8 (8.7) | 22.3 (8.1) | 21.8 (7.8) | 28.3 (10.4) | 26.9 (9.9) | 25.6 (9.6) |
Trunk fat mass (kg)a | 14.1 (5.2) | 13.8 (5.0) | 13.5 (4.9) | 14.3 (5.4) | 13.6 (5.2) | 13.0 (5.1) |
Apolipoprotein A (g/L)a | 1.4 (0.2) | 1.4 (0.2) | 1.4 (0.2) | 1.6 (0.3) | 1.6 (0.3) | 1.7 (0.3) |
Apolipoprotein B (g/L)a | 1.0 (0.2) | 1.0 (0.2) | 1.0 (0.2) | 1.0 (0.2) | 1.0 (0.2) | 1.0 (0.2) |
Apolipoprotein B/Apolipoprotein A-Ia | 0.8 (0.2) | 0.7 (0.2) | 0.7 (0.2) | 0.7 (0.2) | 0.7 (0.2) | 0.6 (0.2) |
Lipoprotein (a) (nmol/L)a | 44.1 (49.3) | 44.0 (49.0) | 43.7 (48.8) | 45.9 (49.8) | 45.3 (49.4) | 44.6 (48.8) |
Total cholesterol (mmol/L)a | 5.5 (1.1) | 5.5 (1.1) | 5.4 (1.1) | 5.9 (1.1) | 5.9 (1.1) | 5.8 (1.1) |
Low-density lipoprotein cholestrol (mmol/L)a | 3.5 (0.9) | 3.5 (0.9) | 3.4 (0.9) | 3.6 (0.9) | 3.7 (0.9) | 3.6 (0.9) |
High-density lipoprotein cholestrol (mmol/L)a | 1.2 (0.3) | 1.3 (0.3) | 1.3 (0.3) | 1.5 (0.4) | 1.6 (0.4) | 1.6 (0.4) |
LDL/HDLa | 2.9 (0.9) | 2.9 (0.9) | 2.8 (0.9) | 2.5 (0.8) | 2.4 (0.8) | 2.3 (0.8) |
TC/HDLa | 4.6 (1.2) | 4.5 (1.1) | 4.3 (1.1) | 4.0 (1.0) | 3.8 (1.0) | 3.7 (1.0) |
Triglycerides (mmol/L)a | 2.2 (1.2) | 1.9 (1.1) | 1.8 (1.0) | 1.8 (1.0) | 1.5 (0.8) | 1.4 (0.8) |
C-reactive protein (mg/L)a | 3.0 (5.0) | 2.3 (4.1) | 2.1 (3.9) | 3.4 (5.0) | 2.6 (4.1) | 2.1 (3.7) |
Systolic blood pressure (mm Hg)a | 143.0 (18.4) | 142.8 (18.5) | 142.3 (18.6) | 137.5 (19.9) | 137.5 (20.3) | 136.5 (20.6) |
Diastolic blood pressure (mm Hg)a | 83.8 (10.5) | 84.1 (10.5) | 84.1 (10.6) | 80.8 (10.5) | 80.7 (10.5) | 80.5 (10.6) |
Duration of moderate activity (min/d)a | 66.0 (88.2) | 63.8 (83.1) | 61.3 (79.2) | 55.1 (69.1) | 56.3 (68.6) | 55.8 (68.5) |
Ever used hormone-replacement therapyb | ||||||
Yes | Â | Â | Â | 40 | 39 | 35 |
Qualificationb | ||||||
 College/uni degree | 30 | 35 | 36 | 28 | 31 | 34 |
Smoking statusb | ||||||
 Never | 43 | 50 | 54 | 57 | 60 | 62 |
 Former | 38 | 39 | 38 | 30 | 32 | 32 |
 Current | 18 | 11 | 8 | 12 | 8 | 6 |
Alcohol consumption statusb | ||||||
 Never | 3 | 3 | 3 | 7 | 6 | 5 |
 Former | 4 | 3 | 3 | 5 | 3 | 3 |
 Current | 92 | 94 | 94 | 88 | 91 | 92 |