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Table 1 Characteristics of UK Biobank study participants by category of circulating total bilirubin levels (N = 467,519)

From: Bilirubin as an indicator of cardiometabolic health: a cross-sectional analysis in the UK Biobank

Baseline characteristic

Total bilirubin tertile

Total bilirubin tertile

1

2

3

1

2

3

Men

Women

n = 71,496

n = 71,270

n = 71,240

n = 84,930

n = 84,185

n = 84,398

Bilirubin levels (μmol/L)Ω

6.7 [5.9; 7.4]

9.1 [8.5; 9.8]

13.2 [11.7; 16.5]

5.4 [4.8; 5.9]

7.3 [6.8; 7.8]

10.4 [9.2; 12.8]

Age (years)a

56.6 (8.2)

56.9 (8.1)

56.8 (8.3)

56.3 (7.9)

56.8 (7.9)

56.0 (8.2)

Weight (kg)a

86.3 (15.1)

86.0 (14.1)

85.5 (13.7)

73.0 (14.7)

71.3 (13.9)

69.9 (13.3)

Height (cm)a

174.9 (6.8)

175.8 (6.8)

176.2 (6.9)

161.8 (6.3)

162.5 (6.3)

163.1 (6.3)

Body mass index (kg/m2)a

28.2 (4.5)

27.8 (4.1)

27.5 (4.0)

27.9 (5.4)

27.0 (5.1)

26.3 (4.9)

Waist circumference (cm)a

97.9 (11.8)

96.8 (11.1)

96.0 (10.9)

86.7 (12.9)

84.5 (12.3)

82.8 (12.0)

Hip circumference (cm)a

103.6 (8.1)

103.4 (7.5)

103.2 (7.2)

104.6 (10.9)

103.3 (10.2)

102.1 (9.8)

Waist-hip ratioa

0.9 (0.1)

0.9 (0.1)

0.9 (0.1)

0.8 (0.1)

0.8 (0.1)

0.8 (0.1)

Fat mass (kg)a

22.8 (8.7)

22.3 (8.1)

21.8 (7.8)

28.3 (10.4)

26.9 (9.9)

25.6 (9.6)

Trunk fat mass (kg)a

14.1 (5.2)

13.8 (5.0)

13.5 (4.9)

14.3 (5.4)

13.6 (5.2)

13.0 (5.1)

Apolipoprotein A (g/L)a

1.4 (0.2)

1.4 (0.2)

1.4 (0.2)

1.6 (0.3)

1.6 (0.3)

1.7 (0.3)

Apolipoprotein B (g/L)a

1.0 (0.2)

1.0 (0.2)

1.0 (0.2)

1.0 (0.2)

1.0 (0.2)

1.0 (0.2)

Apolipoprotein B/Apolipoprotein A-Ia

0.8 (0.2)

0.7 (0.2)

0.7 (0.2)

0.7 (0.2)

0.7 (0.2)

0.6 (0.2)

Lipoprotein (a) (nmol/L)a

44.1 (49.3)

44.0 (49.0)

43.7 (48.8)

45.9 (49.8)

45.3 (49.4)

44.6 (48.8)

Total cholesterol (mmol/L)a

5.5 (1.1)

5.5 (1.1)

5.4 (1.1)

5.9 (1.1)

5.9 (1.1)

5.8 (1.1)

Low-density lipoprotein cholestrol (mmol/L)a

3.5 (0.9)

3.5 (0.9)

3.4 (0.9)

3.6 (0.9)

3.7 (0.9)

3.6 (0.9)

High-density lipoprotein cholestrol (mmol/L)a

1.2 (0.3)

1.3 (0.3)

1.3 (0.3)

1.5 (0.4)

1.6 (0.4)

1.6 (0.4)

LDL/HDLa

2.9 (0.9)

2.9 (0.9)

2.8 (0.9)

2.5 (0.8)

2.4 (0.8)

2.3 (0.8)

TC/HDLa

4.6 (1.2)

4.5 (1.1)

4.3 (1.1)

4.0 (1.0)

3.8 (1.0)

3.7 (1.0)

Triglycerides (mmol/L)a

2.2 (1.2)

1.9 (1.1)

1.8 (1.0)

1.8 (1.0)

1.5 (0.8)

1.4 (0.8)

C-reactive protein (mg/L)a

3.0 (5.0)

2.3 (4.1)

2.1 (3.9)

3.4 (5.0)

2.6 (4.1)

2.1 (3.7)

Systolic blood pressure (mm Hg)a

143.0 (18.4)

142.8 (18.5)

142.3 (18.6)

137.5 (19.9)

137.5 (20.3)

136.5 (20.6)

Diastolic blood pressure (mm Hg)a

83.8 (10.5)

84.1 (10.5)

84.1 (10.6)

80.8 (10.5)

80.7 (10.5)

80.5 (10.6)

Duration of moderate activity (min/d)a

66.0 (88.2)

63.8 (83.1)

61.3 (79.2)

55.1 (69.1)

56.3 (68.6)

55.8 (68.5)

Ever used hormone-replacement therapyb

Yes

   

40

39

35

Qualificationb

 College/uni degree

30

35

36

28

31

34

Smoking statusb

 Never

43

50

54

57

60

62

 Former

38

39

38

30

32

32

 Current

18

11

8

12

8

6

Alcohol consumption statusb

 Never

3

3

3

7

6

5

 Former

4

3

3

5

3

3

 Current

92

94

94

88

91

92

  1. Data are presented as Ω median [interquartile range (25th percentile and the 75th percentile)] for non-normal distributed measures, amean (SD) for continuous measures, b n% for categorical measures
  2. Number of missing data in main outcomes (n): weight (1557), height (1360), waist circumference (999), hip circumference (1054), fat mass (9080), trunk fat mass (8618), apolipoprotein A-I (41,982), apolipoprotein B (2319), lipoprotein (a) (93,429), total cholesterol (140), low-density lipoprotein cholestrol (841), high-density lipoprotein cholestrol (39,571), triglycerides (174), systolic blood pressure (30,099), diastolic blood pressure (30,087)