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Table 3 Risk of myocardial infarction, stroke, heart failure, and mortality according to BARD score in patients with fatty liver index (FLI) ≥ 60 compared to FLI < 60

From: The associations of hepatic steatosis and fibrosis using fatty liver index and BARD score with cardiovascular outcomes and mortality in patients with new-onset type 2 diabetes: a nationwide cohort study

 

Event

Duration (person-years)

Incidence Ratea

Hazard Ratio (95% CI)

Model 1

Model 2

Myocardial infarction

 FLI < 60

2008

704,631

2.85

1 (Ref)

1 (Ref)

 FLI ≥ 60, BARD < 2

457

184,258

2.48

1.13 (1.02–1.26)

1.13 (1.00–1.27)

 FLI ≥ 60, BARD ≥ 2

614

177,722

3.45

1.21 (1.11–1.33)

1.26 (1.14–1.40)

 P for trend

   

 < 0.001

 < 0.001

Stroke

 FLI < 60

2931

701,213

4.18

1 (Ref)

1 (Ref)

 FLI ≥ 60, BARD < 2

490

184,039

2.66

1.02 (0.92–1.12)

1.13 (1.01–1.26)

 FLI ≥ 60, BARD ≥ 2

817

176,836

4.62

1.16 (1.07–1.25)

1.26 (1.15–1.37)

 P for trend

   

 < 0.001

 < 0.001

Heart failure

 FLI < 60

4127

702,724

5.87

1 (Ref)

1 (Ref)

 FLI ≥ 60, BARD < 2

724

184,297

3.93

1.11 (1.02–1.20)

1.10 (1.01–1.21)

 FLI ≥ 60, BARD ≥ 2

1252

177,013

7.07

1.29 1.21–1.38)

1.31 (1.22–1.41)

 P for trend

   

 < 0.001

 < 0.001

Mortality

 FLI < 60

6191

710,862

8.71

1 (Ref)

1 (Ref)

 FLI ≥ 60, BARD < 2

741

185,750

3.99

0.81 (0.75–0.87)

1.22 (1.23–1.33)

 FLI ≥ 60, BARD ≥ 2

1533

179,567

8.54

1.03 (0.97–1.09)

1.48 (1.39–1.58)

 P for trend

   

0.736

 < 0.001

  1. Model 1: Adjusted for age and sex
  2. Model 2: Adjusted for age, sex, smoking status, alcohol consumption, regular exercise, income, body weight, hypertension, dyslipidemia, fasting glucose, and number of oral hypoglycemic agents used
  3. CI, confidence interval
  4. aIncidence per 1000 person-years