| Placebo (n = 191) | Metformin (n = 194) |
---|---|---|
Sex (female) | 95 (50) | 113 (58) |
Age | 59 (11) | 64 (10) |
Currently smoking (yes) | 59 (31) | 37 (19) |
Body mass index (kg/m2) | 29.8 (4.8) | 29.8 (5.1) |
Diabetes duration (years) | 12.2 (7.9) | 14.2 (8.7) |
Cardiovascular history score | 0.9 (1.3) | 1.2 (1.4) |
Systolic blood pressure (mmHg) | 160 (24.8) | 160 (24.1) |
Diastolic blood pressure (mmHg) | 85.7 (11.1) | 85.4 (11.9) |
Blood pressure lowering drugs (yes) | 74 (39) | 91 (47) |
Lipid lowering drugs (yes) | 31 (16) | 32 (17) |
Cardiac Troponin I at baseline | 3.0 [2.0, 5.0] | 3.6 [2.3, 5.5] |
Cardiac Troponin T at baseline | 10.0 [6.7, 14.1] | 10.2 [7.6, 14.2] |
Plasma HbA1c (%, mmol/mol) | 7.9 (1.2) | 7.9 (1.2) |
LDL cholesterol (mmol/l) | 3.4 (1.0) | 3.6(1.1) |
Total cholesterol (mmol/l) | 5.5 (1.2) | 5.6 (1.3) |