Controls (n = 83) | T2DM (AR −) (n = 149) | T2DM (AR +) (n = 66) | |
---|---|---|---|
Age (years) | 62 (55,69) | 58 (52, 65)* | 68 (61, 75)*† |
Gender(% female) | 28 (33.73) | 49 (32.88) | 24 (36.36) |
BMI(kg/m2) | 24.2 (22.6, 26.5) | 24.3 (22.5, 26.4)* | 24.0 (22.9, 26.3) |
Restheart rate (bpm) | 76 (67, 86) | 75 (65, 84) | 77 (70, 88) |
SBP (mmHg) | 120.0 (116.0, 124.0) | 128.0 (116.0, 140.0)* | 128.0 (118.0, 140.5)* |
DBP (mmHg) | 79.0 (70.0, 87.0) | 78.00 (70.0, 87.0) | 80.0 (70.0, 87.0) |
Fasting plasma glucose, mmol/l | – | 8.59 (6.42, 10.65) | 6.97 (5.87, 9.10)† |
HbA1c (%) | – | 7.20 (6.60, 8.28) | 6.70 (6.40, 7.15)† |
Diabetes duration (year) | – | 7.25 (4.00, 12.00) | 8.50 (3.50, 12.00) |
TG (mmol/l) | – | 1.37 (1.05, 2.00) | 1.29 (1.10, 1.60) |
TC (mmol/l) | – | 4.24 (3.54, 5.07) | 3.72 (3.14, 4.79) |
HDL (mmol/l) | – | 1.09 (0.87, 1.35) | 1.21 (1.02, 1.48) |
LDL (mmol/l) | – | 2.42 ± 0.96 | 2.23 ± 0.81 |
Regurgitation degree | |||
Mild, n (%) | – | – | 29 (43.9) |
Moderate, n (%) | – | – | 20 (30.3) |
Severe, n (%) | – | – | 17 (25.8) |
Diabetes related drugs | |||
Biguanides, n (%) | – | 37 (33.6) | 10 (15.2) |
Sulfonylureas, n (%) | – | 21 (19.2) | 19 (28.8) |
α-Glucosides inhibitor, n (%) | – | 24 (21.8) | 20 (30.3) |
GLP-1/DPP-4 inhibitor | – | 7 (6.4) | 5 (7.6) |
Insulinum | – | 14 (12.7) | 12 (18.1) |
Medication unknown | – | 7 (6.3) | 0 |
eGFR (mL/min) | – | 72.3 ± 29.3 | 67.5 ± 19.7 |