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Table 7 Association between the TyG index and the risk of carotid artery plaques according to different glucose regulation state and age

From: Association between triglyceride glucose index and carotid artery plaque in different glucose metabolic states in patients with coronary heart disease: a RCSCD-TCM study in China

Age

Glucose regulation state

Variables

carotid artery plaques

OR (95% CI)a

P-value

OR (95% CI)b

P-value

OR (95% CI)c

P-value

 ≤ 60

Normal glucose regulation

TyG index

1.32 (1.22–1.44)

 < 0.001

1.16 (1.06–1.28)

 < 0.001

1.12 (0.98–1.28)

0.099

Q1

Reference

 

Reference

 

Reference

 

Q2

1.27 (1.14–1.43)

 < 0.001

1.24 (1.10–1.40)

 < 0.001

1.17 (1.02–1.33)

0.026

Q3

1.53 (1.34–1.74)

 < 0.001

1.40 (1.22–1.60)

 < 0.001

1.24 (1.04–1.46)

0.015

Q4

1.38 (1.15–1.64)

 < 0.001

1.09 (0.91–1.32)

0.360

1.11 (0.86–1.43)

0.430

Prediabetes

TyG index

1.05 (0.96–1.15)

0.290

0.99 (0.90–1.09)

0.770

0.93 (0.80–1.09)

0.367

Q1

Reference

 

Reference

 

Reference

 

Q2

0.86 (0.73–1.02)

0.090

0.92 (0.77–1.09)

0.320

0.74 (0.61–0.90)

0.002

Q3

1.21 (1.02–1.43)

0.030

1.12 (0.94–1.34)

0.190

0.86 (0.70–1.05)

0.141

Q4

1.08 (0.91–1.29)

0.390

1.04 (0.87–1.26)

0.650

0.89 (0.69–1.15)

0.374

Diabetes

TyG index

1.21 (1.13–1.30)

 < 0.001

1.16 (1.08–1.25)

 < 0.001

1.21(1.08–1.35)

0.001

Q1

Reference

 

Reference

 

Reference

 

Q2

1.32 (0.98–1.78)

0.070

1.23 (0.91–1.67)

0.190

0.90 (0.64–1.26)

0.544

Q3

1.71 (1.29–2.27)

 < 0.001

1.49 (1.11–2.00)

0.010

0.95 (0.68–1.31)

0.738

Q4

1.98 (1.51–2.60)

 < 0.001

1.69 (1.27–2.24)

 < 0.001

1.03 (0.74–1.43)

0.866

 > 60

Normal glucose regulation

TyG index

0.94 (0.87–1.02)

0.160

1.05 (0.96–1.14)

0.300

0.99 (0.88–1.11)

0.817

Q1

Reference

 

Reference

 

Reference

 

Q2

0.94 (0.86–1.03)

0.200

1.01 (0.92–1.11)

0.780

0.94 (0.85–1.04)

0.241

Q3

0.85 (0.76–0.95)

 < 0.001

0.99 (0.88–1.11)

0.890

0.87 (0.76–1.00)

0.048

Q4

0.90 (0.74–1.10)

0.320

0.95 (0.77–1.17)

0.640

0.90 (0.70–1.16)

0.420

Prediabetes

TyG index

0.98 (0.90–1.07)

0.640

1.03 (0.94–1.13)

0.510

0.96 (0.84–1.10)

0.568

Q1

Reference

 

Reference

 

Reference

 

Q2

1.03 (0.91–1.15)

0.680

1.08 (0.96–1.21)

0.230

0.97 (0.85–1.11)

0.686

Q3

1.09 (0.97–1.23)

0.150

1.19 (1.05–1.35)

0.010

1.01 (0.87–1.17)

0.916

Q4

0.76 (0.66–0.88)

 < 0.001

0.80 (0.69–0.94)

0.010

0.65 (0.52–0.80)

 < 0.001

Diabetes

TyG index

1.38 (1.29–1.47)

 < 0.001

1.43 (1.34–1.53)

 < 0.001

1.35 (1.24–1.48)

 < 0.001

Q1

Reference

 

Reference

 

Reference

 

Q2

1.18 (0.99–1.40)

0.060

1.25 (1.05–1.49)

0.010

1.19 (0.99–1.43)

0.059

Q3

1.15 (0.98–1.35)

0.080

1.25 (1.06–1.47)

0.010

1.05 (0.88–1.25)

0.618

Q4

1.63 (1.39–1.90)

 < 0.001

1.78 (1.52–2.09)

 < 0.001

1.45 (1.21–1.74)

 < 0.001

  1. aModel 1: unadjusted
  2. bModel 2: adjusted for sex, SBP, DBP
  3. cModel 3: adjusted for sex, SBP, DBP, CRP, TC, HDL-C, LDL-C, smoking, drinking, hypertension, hyperlipidemia, use of antihypertensives, and use of antilipidemic
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