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Table 6 Association between the TyG index and the risk of carotid artery plaques according to different glucose regulation state and sex

From: Association between triglyceride glucose index and carotid artery plaque in different glucose metabolic states in patients with coronary heart disease: a RCSCD-TCM study in China

Sex

Glucose regulation state

Variables

Carotid artery plaques

OR (95% CI)a

P-value

OR (95% CI)b

P-value

OR (95% CI)c

P-value

Male

Normal glucose regulation

TyG index

0.88 (0.81–0.96)

0.005

1.24 (1.13–1.36)

 < 0.001

1.21 (1.06–1.39)

0.005

Q1

Reference

 

Reference

 

Reference

 

Q2

0.98 (0.88–1.10)

0.751

1.23 (1.09–1.38)

0.001

1.06 (0.93–1.21)

0.398

Q3

0.79 (0.69–0.90)

 < 0.001

1.10 (0.96–1.27)

0.182

0.83 (0.70–0.96)

0.033

Q4

0.57 (0.48–0.68)

 < 0.001

1.00 (0.82–1.22)

0.974

0.91 (0.69–1.19)

0.494

Prediabetes

TyG index

0.67 (0.61–0.74)

 < 0.001

0.97 (0.87–1.07)

0.505

0.95 (0.82–1.12)

0.557

Q1

Reference

 

Reference

 

Reference

 

Q2

0.94 (0.81–1.10)

0.420

1.05 (0.89–1.24)

0.552

0.94 (0.79–1.12)

0.511

Q3

0.85 (0.73–0.99)

0.038

1.18 (1.00–1.39)

0.055

1.02 (0.84–1.23)

0.846

Q4

0.49 (0.42–0.58)

 < 0.001

0.83 (0.69–1.00)

0.045

0.67 (0.52–0.86)

0.002

Diabetes

TyG index

0.91 (0.84–0.97)

0.005

1.11 (1.03–1.19)

0.009

1.23 (1.10–1.37)

 < 0.001

Q1

Reference

 

Reference

 

Reference

 

Q2

0.99 (0.78–1.24)

0.904

1.19 (0.94–1.51)

0.143

1.13 (0.88–1.45)

0.331

Q3

1.06 (0.85–1.32)

0.592

1.34 (1.07–1.67)

0.011

1.13 (0.90–1.44)

0.284

Q4

0.98 (0.79–1.20)

0.821

1.48 (1.19–1.84)

 < 0.001

1.37 (1.08–1.74)

0.010

Female

Normal glucose regulation

TyG index

1.05 (0.97–1.14)

0.198

1.09 (1.00–1.19)

0.046

1.02 (0.90–1.15)

0.794

Q1

Reference

 

Reference

 

Reference

 

Q2

1.06 (0.97–1.15)

0.223

1.04 (0.94–1.14)

0.469

1.01 (0.91–1.23)

0.825

Q3

1.17 (1.06–1.30)

0.003

1.22 (1.09–1.37)

0.001

1.16 (1.01–1.33)

0.043

Q4

1.03 (0.86–1.24)

0.739

1.23 (1.01–1.5)

0.041

1.22 (0.95–1.56)

0.115

Prediabetes

TyG index

1.05 (0.97–1.14)

0.244

1.14 (1.04–1.24)

0.005

1.17 (1.02–1.35)

0.023

Q1

Reference

 

Reference

 

Reference

 

Q2

0.94 (0.84–1.06)

0.327

1.05 (0.93–1.20)

0.410

0.93 (0.81–1.07)

0.336

Q3

1.22 (1.08–1.38)

0.001

1.26 (1.11–1.44)

 < 0.001

1.10 (0.94–1.29)

0.222

Q4

0.89 (0.77–1.03)

0.127

1.12 (0.96–1.31)

0.145

1.12 (0.89–1.40)

0.328

Diabetes

TyG index

1.44 (1.35–1.53)

 < 0.001

1.58 (1.48–1.69)

 < 0.001

1.45 (1.32–1.60)

 < 0.001

Q1

Reference

 

Reference

 

Reference

 

Q2

1.31 (1.08–1.59)

0.005

1.30 (1.06–1.59)

0.012

1.14 (0.91–1.42)

0.261

Q3

1.44 (1.21–1.73)

 < 0.001

1.38 (1.14–1.67)

0.001

1.01 (0.82–1.25)

0.930

Q4

1.97 (1.65–2.34)

 < 0.001

2.15 (1.78–2.58)

 < 0.001

1.42 (1.14–1.77)

0.002

  1. aModel 1: unadjusted
  2. bModel 2: adjusted for age, SBP, DBP
  3. cModel 3: adjusted for age, SBP, DBP, CRP, TC, HDL-C, LDL-C, smoking, drinking, hypertension, hyperlipidemia, use of antihypertensives, and use of antilipidemic
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Cardiovascular Diabetology

ISSN: 1475-2840