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Table 3 Comparison of CMR-derived parameters among normal controls, T2DM patients with and without CAD

From: The adverse impact of coronary artery disease on left ventricle systolic and diastolic function in patients with type 2 diabetes mellitus: a 3.0T CMR study

 

Normal controls

T2DM

(n = 83)

T2DM (CAD −) (n = 178)

T2DM (CAD +) (n = 104)

LV geometry and function

 LVEDVI (mL/m2)

79.0 (67.0, 87.7)

89.3 (74.6, 117.5)*

106.5 (79.0, 141.4)

 LVESVI (mL/m2)

28.0 (23.9, 33.1)

37.5 (26.9, 72.9)*

59.2 (36.1, 107.8)

 LVSVI (mL/m2)

49.8 (42.3, 54.4)

46.7 (35.5, 55.5)

40.1 (32.0, 48.6)

 LVEF (%)

63.1 (58.0, 67.8)

55.1 (40.5, 63.5)*

37.2 (27.0, 52.4)

 LVMI (g/m2)

42.0 (35.4, 47.5)

51.5 (43.1, 68.4)*

59.3 (50.1, 66.6)*

PS (%)

 GRPS

35.3 (30.4, 38.8)

24.2 (13.4, 33.6) *

18.1 (9.5, 23.9)

 GCPS

 − 20.8 (− 22.2, − 19.1)

 − 16.9 (− 20.7, − 10.6) *

 − 12.2 (− 16.3, − 7.5)

 GLPS

 − 14.4 (− 16.7, − 12.2)

 − 10.0 (− 12.5, − 5.9) *

 − 7.8 (− 10.0, − 5.2)

PSSR (1/s)

 Radial

2.0 (1.7, 2.4)

1.4 (0.7, 1.9)*

1.0 (0.6, 1.5)

 Circumferential

 − 1.0 (− 1.2, − 0.9)

 − 0.9 (− 1.1, − 0.6)*

 − 0.7 (− 0.8, − 0.5)

 Longitudinal

 − 0.8 (− 0.9, − 0.6)

 − 0.7 (− 0.8, − 0.4)*

 − 0.5 (− 0.7, − 0.4)

PDSR (1/s)

 Radial

 − 2.5 (− 3.1, − 2.0)

 − 1.5 (− 2.1, − 0.8)*

 − 1.1 (− 1.5, − 0.6)

 Circumferential

1.3 (1.1, 1.5)

0.9 (0.6, 1.1)*

0.7 (0.5, 0.9)

 Longitudinal

0.9 (0.7, 1.1)

0.6 (0.5, 0.8)*

0.6 (0.4, 0.7) *

LGE

 LGE, n (%)

56 (31.5%)

104 (100%) §

 LGE rel (%)

7.7 (4.1, 16.8) %

22.6 (12.9, 46.3)% §

  1. All values are presented as n (%) or median (Q1-Q3). “” indicates the direction of strains. LV left ventricular, EF ejection fraction, EDV end-diastolic volume, ESV end-systolic volume, SV stroke-volume, I indexed to BSA, PS peak strain, GRPS global radial peak strain, GCPS global circumferential peak strain, GLPS global longitudinal peak strain, PSSR peak systolic strain rate, PDSR peak diastolic strain rate, LGE late gadolinium enhancement
  2. *P < 0.017 vs. normal group; §P < 0.017 vs. T2DM (CAD-) group