Endpoints | No. of events (%) | Hazard ratio (95% confidence interval) | P value | Adjusted hazard ratio (95% confidence interval) | Adjusted P value |
---|---|---|---|---|---|
Primary endpoint | |||||
 MACE | |||||
  Tertile 1 | 88 (4.8) | Ref | Ref | Ref | Ref |
  Tertile 2 | 85 (4.6) | 0.96 (0.71–1.30) | 0.801 | 0.93 (0.69–1.27) | 0.656 |
  Tertile 3 | 120 (6.5) | 1.37 (1.04–1.81) | 0.025* | 1.36 (1.01–1.82) | 0.042* |
Secondary endpoint | |||||
 Cardiac death/MI | |||||
  Tertile 1 | 20 (1.1) | Ref | Ref | Ref | Ref |
  Tertile 2 | 21 (1.1) | 1.03 (0.56–1.91) | 0.919 | 1.10 (0.59–2.06) | 0.766 |
  Tertile 3 | 36 (2.0) | 1.81 (1.05–3.13) | 0.033* | 2.10 (1.17–3.78) | 0.013* |
 All-cause death | |||||
  Tertile 1 | 27 (1.5) | Ref | Ref | Ref | Ref |
  Tertile 2 | 23 (1.2) | 0.83 (0.48–1.46) | 0.521 | 1.00 (0.55–1.80) | 0.993 |
  Tertile 3 | 13 (0.7) | 0.48 (0.25–0.93) | 0.029* | 0.60 (0.29–1.24) | 0.169 |
 Cardiac death | |||||
  Tertile 1 | 14 (0.7) | Ref | Ref | Ref | Ref |
  Tertile 2 | 9 (0.5) | 0.61 (0.27–1.42) | 0.256 | 0.88 (0.37–2.13) | 0.777 |
  Tertile 3 | 9 (0.5) | 0.64 (0.28–1.47) | 0.289 | 1.10 (0.45–2.71) | 0.828 |
 TVR | |||||
  Tertile 1 | 70 (3.8) | Ref | Ref | Ref | Ref |
  Tertile 2 | 72 (3.9) | 1.03 (0.74–1.43) | 0.866 | 0.98 (0.70–1.37) | 0.903 |
  Tertile 3 | 105 (5.7) | 1.51 (1.11–2.03) | 0.008* | 1.40 (1.01–1.93) | 0.042* |
 Stroke | |||||
  Tertile 1 | 32 (1.7) | Ref | Ref | Ref | Ref |
  Tertile 2 | 23 (1.2) | 0.69 (0.40–1.18) | 0.176 | 0.75 (0.42–1.33) | 0.319 |
  Tertile 3 | 27 (1.5) | 0.83 (0.50–1.39) | 0.478 | 1.01 (0.58–1.75) | 0.973 |
 Myocardial infarction | |||||
  Tertile 1 | 12 (0.7) | Ref | Ref | Ref | Ref |
  Tertile 2 | 15 (0.8) | 1.26 (0.59–2.67) | 0.564 | 1.23 (0.57–2.66) | 0.605 |
  Tertile 3 | 32 (1.7) | 2.69 (1.38–5.22) | 0.004* | 2.82 (1.39–5.72) | 0.004* |