From: Plasma apolipoprotein concentrations and incident diabetes in subjects with prediabetes
Apolipoproteins | All (n = 307) | No diabetes (n1 = 192) | New-onset diabetes (n2 = 115) | OR (95% CI) | p-value | Data available (n1/n2) |
---|---|---|---|---|---|---|
Total cholesterol (mg/dL) | 217 ± 40 | 218 ± 40 | 215 ± 40 | 0.93 (0.74–1.17) | 0.5486 | 191/114 |
Triglycerides (mg/dL) | 119 [86; 167] | 108 [83; 154] | 137 [94; 173] | 1.33 (1.05–1.69) | 0.0199* | 191/113 |
LDL-C (mg/dL) | 137 ± 36 | 138 ± 37 | 136 ± 35 | 0.96 (0.76–1.21) | 0.7202 | 188/112 |
HDL-C (mg/dL) | 53 ± 15 | 55 ± 16 | 50 ± 13 | 0.79 (0.62–1.00) | 0.0461* | 191/113 |
Non-HDL-C (mg/dL) | 164 ± 41 | 164 ± 42 | 164 ± 38 | 1.03 (0.82–1.31) | 0.7794 | 191/113 |
ApoA-I (mg/dL) | 123 [106; 143] | 124 [106; 144] | 122 [106; 142] | 0.93 (0.74–1.17) | 0.5269 | 192/115 |
ApoA-II (mg/dL) | 22.7 [19.1; 27.9] | 22.3 [19.1; 27.8] | 23.4 [19.2; 28.1] | 1.08 (0.86–1.36) | 0.5158 | 192/115 |
ApoA-IV (mg/dL) | 8.4 [6.3; 10.8] | 8.4 [6.4; 10.8] | 8.5 [5.9; 10.7] | 0.99 (0.79–1.25) | 0.9469 | 192/115 |
ApoB100 (mg/dL) | 56.0 [43.5; 71.2] | 56.5 [45.0; 71.7] | 53.7 [41.9; 68.9] | 0.94 (0.75–1.19) | 0.6266 | 192/115 |
ApoC-I (mg/dL) | 1.12 [0.92; 1.44] | 1.12 [0.89; 1.38] | 1.13 [0.94; 1.53] | 1.17 (0.93–1.47) | 0.1766 | 192/115 |
ApoC-II (mg/dL) | 2.63 [1.92; 3.48] | 2.46 [1.88; 3.48] | 2.84 [2.08; 3.62] | 1.35 (1.06–1.70) | 0.0133* | 192/115 |
ApoC-III (mg/dL) | 6.22 [4.91; 8.01] | 6.04 [4.88; 7.51] | 6.73 [5.23; 9.22] | 1.27 (1.01–1.61) | 0.0430* | 192/115 |
ApoC-IV (mg/dL) | 0.0 [0.0; 0.12] | 0.0 [0.0; 0.13] | 0.0 [0.0; 0.11] | 1.03 (0.82–1.29) | 0.8204 | 192/115 |
ApoD (mg/dL) | 2.88 [2.37; 3.55] | 2.98 [2.43; 3.65] | 2.78 [2.35; 3.30] | 0.86 (0.68–1.09) | 0.2026 | 192/115 |
ApoE (mg/dL) | 6.96 [5.61; 8.61] | 6.45 [5.44; 8.35] | 7.61 [6.11; 9.14] | 1.31 (1.04–1.66) | 0.0232* | 192/115 |
ApoF (mg/dL) | 0.82 [0.46; 1.20] | 0.79 [0.46; 1.14] | 0.90 [0.48; 1.36] | 1.22 (0.96–1.53) | 0.0994 | 192/115 |
ApoH (mg/dL) | 4.66 [3.95; 5.52] | 4.47 [3.88; 5.42] | 4.77 [4.14; 5.94] | 1.25 (0.98–1.58) | 0.0670 | 192/115 |
ApoJ (mg/dL) | 7.96 [6.66; 9.44] | 7.83 [6.66; 9.26] | 8.43 [6.65; 9.77] | 1.26 (1.00–1.60) | 0.0502 | 192/115 |
ApoL1 (mg/dL) | 1.12 [0.92; 1.35] | 1.09 [0.91; 1.28] | 1.20 [0.95; 1.52] | 1.43 (1.13–1.81) | 0.0032** | 192/115 |
ApoM (mg/dL) | 1.85 [1.50; 2.32] | 1.85 [1.55; 2.33] | 1.85 [1.45; 2.28] | 0.91 (0.71–1.16) | 0.4447 | 192/115 |
Apo(a) (nmol/L) | 22.7 [0.0; 62.4] | 22.8 [0.0; 60.9] | 21.9 [0.0; 64.1] | 1.02 (0.81–1.29) | 0.8685 | 192/115 |