Table 2 Hazard ratios and 95% confidence intervals (CIs) of PAD by quartiles of FPG variability (CV, SD, and VIM)
| Â | N | Events (n) | Follow-up duration (person-years) | Hazard ratio (95% CI) | ||||
|---|---|---|---|---|---|---|---|---|
Unadjusted | Model 1 | Model 2 | Model 3 | Model 4 | ||||
FPG variability (CV) | ||||||||
 Q1 | 38,246 | 4162 | 298,563 | 1 | 1 | 1 | 1 | 1 |
 Q2 | 38,219 | 3898 | 299,318 | 0.94 (0.90, 0.98) | 1.01 (0.96, 1.05) | 1.00 (0.96, 1.05) | 1.00 (0.95, 1.04) | 1.00 (0.95, 1.04) |
 Q3 | 38,231 | 4171 | 297,885 | 1.01 (0.96, 1.05) | 1.08 (1.04, 1.13) | 1.07 (1.03, 1.12) | 1.07 (1.02, 1.12) | 1.07 (1.02, 1.12) |
 Q4 | 38,235 | 4632 | 293,916 | 1.13 (1.08, 1.18) | 1.15 (1.11, 1.20) | 1.14 (1.09, 1.19) | 1.12 (1.07, 1.17) | 1.11 (1.07, 1.16) |
P for trend |  |  | < 0.001 | < 0.001 | < 0.001 | < 0.001 | < 0.001 | |
FPG variability (SD) | ||||||||
 Q1 | 38,234 | 4119 | 298,809 | 1 | 1 | 1 | 1 | 1 |
 Q2 | 38,306 | 3944 | 299,810 | 0.96 (0.91, 1.00) | 1.02 (0.98, 1.07) | 1.02 (0.97, 1.06) | 1.01 (0.97, 1.06) | 1.01 (0.97, 1.06) |
 Q3 | 38,157 | 4119 | 297,664 | 1.00 (0.96, 1.05) | 1.08 (1.03, 1.13) | 1.07 (1.02, 1.11) | 1.05 (1.01, 1.10) | 1.05 (1.01, 1.10) |
 Q4 | 38,234 | 4681 | 293,400 | 1.16 (1.11, 1.21) | 1.18 (1.13, 1.23) | 1.15 (1.11, 1.20) | 1.12 (1.07, 1.17) | 1.11 (1.06, 1.16) |
P for trend |  |  | < 0.001 | < 0.001 | < 0.001 | < 0.001 | < 0.001 | |
FPG variability (VIM) | ||||||||
 Q1 | 38,232 | 4196 | 298,180 | 1 | 1 | 1 | 1 | 1 |
 Q2 | 38,233 | 3970 | 298,826 | 0.95 (0.91, 0.99) | 1.01 (0.97, 1.06) | 1.01 (0.97, 1.05) | 1.00 (0.96, 1.05) | 1.01 (0.96, 1.05) |
 Q3 | 38,233 | 4132 | 298,022 | 0.99 (0.94, 1.03) | 1.07 (1.02, 1.12) | 1.07 (1.02, 1.11) | 1.07 (1.02, 1.11) | 1.07 (1.03, 1.12) |
 Q4 | 38,233 | 4565 | 294,654 | 1.10 (1.06, 1.15) | 1.13 (1.08, 1.18) | 1.13 (1.08, 1.17) | 1.11 (1.07, 1.16) | 1.11 (1.07, 1.16) |
P for trend |  |  | < 0.001 | < 0.001 | < 0.001 | < 0.001 | <  0.001 | |