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Table 1 Baseline characteristics of the participants according to the fasting plasma glucose variability (coefficient of variation)

From: Implications of fasting plasma glucose variability on the risk of incident peripheral artery disease in a population without diabetes: a nationwide population-based cohort study

 

Q1

Q2

Q3

Q4

P value

CV range (%)

4.32 ± 1.47

8.02 ± 0.93

11.53 ± 1.16

19.61 ± 8.74

< 0.001

N

38,246

38,219

38,231

38,235

 

Age (years)

55.83 ± 8.77

54.93 ± 8.34

55.08 ± 8.46

56.13 ± 8.95

< 0.001

Sex (male) (n, %)

19,959 (52.19)

22,325 (58.41)

23,421 (61.26)

24,928 (65.2)

< 0.0001

Body mass index (kg/m2)

23.82 ± 2.76

23.85 ± 2.81

23.85 ± 2.81

23.87 ± 2.89

0.208

Systolic BP (mmHg)

124.35 ± 15.48

124.55 ± 15.48

125.08 ± 15.48

126.6 ± 15.84

< 0.001

Diastolic BP (mmHg)

77.44 ± 10.1

77.83 ± 10.13

78.27 ± 10.2

79.04 ± 10.24

< 0.001

AST (IU/L)

25.39 ± 14.34

25.67 ± 14.08

26 ± 13.53

26.93 ± 16.7

< 0.001

ALT (IU/L)

24.08 ± 18.59

24.58 ± 18.82

24.82 ± 18.29

25.46 ± 19.47

< 0.001

GGT (IU/L)

33.45 ± 41.02

35.88 ± 44.34

37.61 ± 46.57

41.42 ± 54.19

< 0.001

Total cholesterol (mg/dL)

198.34 ± 35.37

198.26 ± 35.74

198.5 ± 35.89

198.8 ± 36.71

0.166

Mean FPG (mmol/L)

5.11 ± 0.51

5.08 ± 0.50

5.08 ± 0.49

5.31 ± 0.84

< 0.001

Smoking status (n, %)

    

< 0.001

 Non-smoker

26,256 (68.65)

25,178 (65.88)

24,528 (64.16)

23,518 (61.51)

 

 Ex-smoker

3497 (9.14)

3525 (9.22)

3439 (9)

3209 (8.39)

 

 Current smoker

5574 (14.57)

6591 (17.25)

7250 (18.96)

8658 (22.64)

 

 Unknown

2919 (7.63)

2925 (7.65)

3014 (7.88)

2850 (7.45)

 

Alcohol consumption (n, %)

    

< 0.001

 Non-drinker

27,831 (72.77)

26,956 (70.53)

26,367 (68.97)

25,799 (67.47)

 

 Drinker

9295 (24.3)

10,277 (26.89)

10,892 (28.49)

11,640 (30.44)

 

 Unknown

1,120 (2.93)

986 (2.58)

972 (2.54)

796 (2.08)

 

Regular exercise (n, %)

    

< 0.001

 None

16,582 (43.36)

16,787 (43.92)

17,246 (45.11)

18,412 (48.15)

 

 Regular exercise

20,531 (53.68)

20,366 (53.29)

20,015 (52.35)

18,983 (49.65)

 

 Unknown

1133 (2.96)

1066 (2.79)

970 (2.54)

840 (2.2)

 

Income (lower 20%)

4738 (12.39)

5130 (13.42)

5577 (14.59)

6387 (16.7)

< 0.001

IFG (%)

8465 (22.13)

9249 (24.2)

10,958 (28.66)

14,758 (38.6)

< 0.001

Hypertension

13,977 (36.54)

13,829 (36.18)

14,216 (37.18)

15,796 (41.31)

< 0.001

Dyslipidemia

7707 (20.15)

7551 (19.76)

7643 (19.99)

7933 (20.75)

0.005

History of stroke

200 (0.52)

173 (0.45)

187 (0.49)

215 (0.56)

0.172

History of chronic kidney disease

135 (0.35)

101 (0.26)

121 (0.32)

119 (0.31)

0.179

History of coronary artery disease

396 (1.04)

403 (1.05)

356 (0.93)

433 (1.13)

0.053

History of congestive heart failure

38 (0.1)

37 (0.1)

41 (0.11)

57 (0.15)

0.110

Use of anti-hypertension medication

14,441 (37.76)

14,002 (36.64)

14,023 (36.68)

15,298 (40.01)

< 0.001

Use of anti-dyslipidemia agent

4968 (12.99)

4774 (12.49)

4688 (12.26)

5053 (13.22)

< 0.001

  1. P-value using ANOVA and Chi-square tests
  2. Data are expressed as mean ± SD, or n (%)
  3. CV: coefficient of variation; BP: blood pressure; AST: aspartate aminotransferase; ALT: alanine aminotransferase; GGT: γ-glutamyl transferase; FPG: fasting plasma glucose; IFG: impaired fasting glucose