Variable | Total | Tertile 1 | Tertile 2 | Tertile 3 | P-value |
---|---|---|---|---|---|
N | 662 | 221 | 221 | 220 | – |
General conditions | |||||
Age, years | 81.87 ± 2.14 | 81.88 ± 2.04 | 82.15 ± 2.38 | 81.58 ± 1.94 | 0.062 |
Female, n (%) | 186 (28.10%) | 35 (15.84%) | 61 (27.60%) | 90 (40.91%) |  < 0.001 |
Height, cm | 165.32 ± 8.25 | 166.36 ± 7.50 | 165.32 ± 8.72 | 164.28 ± 8.39 | 0.025 |
Weight, kg | 67.20 ± 10.68 | 66.52 ± 10.73 | 67.31 ± 10.26 | 67.76 ± 11.06 | 0.463 |
BMI, kg/m2 | 24.57 ± 3.40 | 24.01 ± 3.40 | 24.62 ± 3.30 | 25.07 ± 3.43 | 0.004 |
HR, beat/min | 74.81 ± 14.02 | 73.15 ± 13.54 | 74.13 ± 12.27 | 77.15 ± 15.79 | 0.008 |
SBP, mmHg | 137.08 ± 21.79 | 136.85 ± 22.00 | 137.33 ± 21.04 | 137.06 ± 22.40 | 0.902 |
DBP, mmHg | 71.44 ± 12.12 | 71.96 ± 11.83 | 71.19 ± 11.94 | 71.15 ± 12.60 | 0.731 |
LVEF, % | 55.65 ± 9.91 | 57.06 ± 9.42 | 55.08 ± 10.12 | 54.82 ± 10.06 | 0.034 |
Gensini score | 53.65 ± 42.65 | 40.79 ± 34.51 | 59.78 ± 41.27 | 60.41 ± 48.29 |  < 0.001 |
Risk factors, n (%) | |||||
Hypertension | 511 (77.19%) | 158 (71.49%) | 173 (78.28%) | 180 (81.82%) | 0.032 |
Diabetes | 231 (34.89%) | 46 (20.81%) | 68 (30.77%) | 117 (53.18%) |  < 0.001 |
Hyperlipidemia | 151 (22.81%) | 36 (16.29%) | 54(24.43%) | 61 (27.73%) | 0.011 |
Previous MI | 120 (18.13%) | 34 (15.38%) | 44 (19.91%) | 42 (19.09%) | 0.421 |
Previous stroke | 138 (20.85%) | 43 (19.46%) | 46 (20.81%) | 49 (22.27%) | 0.042 |
CKD | 78 (11.78%) | 19 (8.60%) | 29 (13.12%) | 30 (13.64%) | 0.195 |
Current smoking | 164 (24.77%) | 67 (30.32%) | 47 (21.27%) | 50 (22.73%) | 0.061 |
Baseline blood features | |||||
TC, mmol/L | 4.11 ± 0.97 | 3.87 ± 0.89 | 4.10 ± 0.91 | 4.36 ± 1.04 |  < 0.001 |
TG, mmol/L | 1.39 ± 0.72 | 0.84 ± 0.22 | 1.28 ± 0.33 | 2.04 ± 0.82 |  < 0.001 |
LDL-C, mmol/L | 2.36 ± 0.84 | 2.19 ± 0.75 | 2.38 ± 0.82 | 2.52 ± 0.91 |  < 0.001 |
HDL-C, mmol/L | 1.13 ± 0.36 | 1.23 ± 0.40 | 1.13 ± 0.36 | 1.01 ± 0.28 |  < 0.001 |
eGFR, mL/min/1.73 m2 | 70.85 ± 23.11 | 73.69 ± 17.27 | 69.93 ± 19.77 | 68.93 ± 30.11 | 0.003 |
FBG, mmol/L | 7.05 ± 4.13 | 5.32 ± 1.17 | 6.42 ± 1.75 | 9.40 ± 6.17 |  < 0.001 |
UA, umol/L | 351.59 ± 149.66 | 335.69 ± 200.17 | 356.29 ± 103.22 | 362.85 ± 127.46 | 0.001 |
TyG index | 8.76 ± 0.72 | 8.08 ± 0.61 | 8.72 ± 0.15 | 9.47 ± 0.42 |  < 0.001 |
Cardiovascular medications, n (%) | |||||
Aspirin | 642 (96.98%) | 210 (95.02%) | 217 (98.19%) | 215 (97.73%) | 0.110 |
Clopidogrel | 632 (95.47%) | 208 (94.12%) | 216 (97.74%) | 208 (94.55%) | 0.136 |
Statin | 615 (92.90%) | 206 (93.21%) | 203 (91.86%) | 206 (93.64%) | 0.748 |
β-blocker | 418 (63.14%) | 122 (55.20%) | 147 (66.52%) | 149 (67.73%) | 0.011 |
ACEI/ARB | 364 (54.98%) | 107 (48.42%) | 126 (57.01%) | 124 (59.55%) | 0.040 |
Angiography, n (%) | |||||
LAD lesion | 560 (84.59%) | 184 (83.26%) | 192 (86.88%) | 184 (83.64%) | 0.511 |
LCX lesion | 383 (57.85%) | 129 (58.37%) | 128 (57.92%) | 126 (57.27%) | 0.601 |
RCA lesion | 429 (64.80%) | 144 (65.16%) | 137 (61.99%) | 148 (67.27%) | 0.251 |
LM lesion | 109 (16.47%) | 26 (11.76%) | 39 (17.65%) | 44 (20.00%) | 0.056 |
Multivessel lesion | 466 (70.39%) | 138 (62.44%) | 164 (74.21%) | 164 (74.55%) | 0.007 |
Treatment, n (%) | 0.081 | ||||
Intensive medication | 241 (36.40%) | 94 (42.53%) | 71 (32.13%) | 76 (34.55%) | |
PCI | 405 (61.18%) | 125 (56.56%) | 142 (64.25%) | 138 (62.73%) | |
CABG | 16 (2.42%) | 2 (0.90%) | 8 (3.62%) | 6 (2.73%) |