Table 1 Baseline characteristics of cohort by lower extremity amputation (LEA) status and diabetes status
| Â | LEA cases | Non-cases | Diabetes | No diabetes |
|---|---|---|---|---|
Number of subjects | 656 (1.0%) | 62,478 (99.0%) | 5616 (8.9%) | 57,518 (91.1%) |
 Men | 318 (48.5%) | 27,562 (44.1%) | 2374 (42.3%) | 25,506 (44.3%) |
 Women | 338 (51.5%) | 34,916 (55.9%) | 3242 (57.7%) | 32,012 (55.7%) |
Age (year), mean (SD) | 59.4 (7.9) | 56.5 (8.0) | 60.0 (7.7) | 56.2 (8.0) |
Dialect | ||||
 Hokkien | 256 (39.0%) | 28,983 (46.4%) | 2588 (46.1%) | 26,651 (46.3%) |
 Cantonese | 400 (61.0%) | 33,495 (53.6%) | 3028 (53.9%) | 30,867 (53.7%) |
Level of education | ||||
 No formal education | 267 (40.7%) | 17,028 (27.2%) | 1980 (35.3%) | 15,315 (26.6%) |
 Primary school | 271 (41.3%) | 27,713 (44.4%) | 2461 (43.8%) | 25,523 (44.4%) |
 Secondary or higher | 118 (18.0%) | 17,737 (29.4%) | 1175 (20.9%) | 16,680 (29.0%) |
Physical activity | ||||
 < 0.5 h/wk | 466 (71.0%) | 41,910 (67.1%) | 3928 (69.9%) | 38,448 (66.8%) |
 0.5 to < 4 h/wk | 108 (16.5%) | 12,644 (20.2%) | 1030 (18.4%) | 11,722 (20.4%) |
 ≥ 4 h/wk | 82 (12.5%) | 7924 (12.7%) | 658 (11.7%) | 7348 (12.8%) |
BMI (kg/m2), mean (SD) | 23.9 (3.3) | 23.1 (3.3) | 24.0 (3.3) | 23.0 (3.3) |
Smoking | ||||
 Never | 408 (62.2%) | 43,463 (69.6%) | 3839 (68.4%) | 40,032 (69.6%) |
 Former | 90 (13.7%) | 6873 (11.0%) | 884 (15.7%) | 6079 (10.6%) |
 Current | 158 (24.1%) | 12,142 (19.4%) | 893 (15.9%) | 11,407 (19.8%) |
Alcohol drinking | ||||
 Never/monthly | 584 (89.0%) | 55,244 (88.4%) | 5233 (93.2%) | 50,595 (88.0%) |
 Weekly/daily | 72 (11.0%) | 7234 (11.6%) | 383 (6.8%) | 6923 (12.0%) |
Medical history | ||||
 Diabetes | 346 (52.7%) | 5270 (8.4%) | – | – |
 Hypertension | 225 (34.3%) | 14,782 (23.7%) | 2663 (47.4%) | 12,344 (21.5%) |
 Coronary artery disease | 53 (8.1%) | 2528 (4.1%) | 688 (12.3%) | 1893 (3.3%) |
 Stroke | 31 (4.7%) | 909 (1.5%) | 268 (4.8%) | 672 (1.2%) |